13. How many possible stereoisomers are there for Crestor® (rosuvastatin), a medication used to reducecholesterol?OSNON.NMEMVega. 2ننےb. 4c. 6d. 8OH OHCO₂H

We have been asked to find out the total number of stereoisomers of the given compound.

Answered: 13. How many possible stereoisomers are…

Science

Chemistry

13. How many possible stereoisomers are there for Crestor Ⓡ (rosuvastatin), a medication used to reduce cholesterol?

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter5: Stereochemistry At Tetrahedral Centers

Section5.SE: Something Extra

Problem 62AP

See similar textbooks

Related questions

Q: CI H Classify the compound shown here. A) aldehyde B) ketone alcohol D) ester E) alkane

A: Given structure is: The functional group is

Q: Question 10 An atom of which of the following elements has the largest ionization energy? OB ОК 00 O…

A: The atom which has the largest ionisation energy = ?

Q: 9. Which of the following solutions for a weak acid at equilibrium would have the largest pH? b. 3.2…

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: O CH3 1) LOA, THE - 78°C 2) CH₂I F

A: At lower temperature kinetic product of the reaction favour and hence we got the below product.

Q: 6. 7. 8. OH Naon CO2 H30+ Воз, ревоз Br2, Sa, tel 4 ΟΥ Fe, Hel, 4 HNO2, H₂SO4 Curl A S03, W₂504 NO.…

Q: First, we make sure we have isomers by performing the steps in Table I. Then, we go on to determine…

A: Isomers are the compound having the same molecular formula but different structures. Isomers are…

Q: Please provide a synthesis for the target molecule given the fragments. Please include the reagents…

A: We have to synthesis the target molecule from the given fragments.

Q: Which one or more of the following equations is (are) balanced? (Select all that apply.) O C7H16 +…

Q: For the diprotic weak acid H₂A, Kal = 2.8 x 10-6 M and K₁2 = 8.9 x 109 M. What is the pH of a 0.0450…

A: Introduction : Diprotic acid are those acids which produces two moles of hydrogen when they are…

Q: Which of the following equations are balanced? (Select all that apply.) O C4H10 + 9 0₂ → 4 CO₂ + 5…

Q: HO t Br of CI

A: Given,

Q: a) Calculate AGxn for the reaction (AHrxn=572 kJ; ASrxn° = 179 J/K).

A: We know ∆Gorxn = ∆Hrxno - T∆Srxno . For a reaction to be spontaneous ∆G should be -ve . At…

Q: 17. Which of the following is a mechanism for an SN2 reaction? 1. III. a. I b. II c. III d. IV e.…

A: In SN2 type reaction there is no formation of intermediate. Removal of leaving group and addition of…

Q: Consider the molecular orbital model of Toluene. In the ground state how many molecular orbitals are…

Q: What is the starting material? 1. NaOEt, EtOH 2. 3. NaOH, A 4. H₂O, A OH

A: The organic reaction is given and question asked for the starting material of this reaction.

Q: Given the following reaction and its equilibrium constant at a certain temperature: N₂(g) + 3H₂(g)…

Q: ! 1 F1 A: D: G: Q. No. III). G4 JA BY- O In the following road-map problem, identify the structures…

Q: 10. Predict the product for the following reaction. b. Loicroi Il 4.CHICHICHAGSreter c. Ill d. IV e.…

Q: n Which of the following best describes Osmolarity? O a. Related to the total number of ionic…

A: Osmolarity is define as follow.

Q: Using the isomers classification flowchart given above, categorize each pair of structures using all…

Q: Exercises 1. Describe a procedure that could be used to identify the limiting component in a…

A: In this question we have to tell that how can we distinguish the limiting reagent in a chemical…

Q: why electronegativity and ionization energy have the same way in the periodic table trend

A: Electronegativity and ionization energy have same trend in periodic table , they increases from left…

Q: Draw an arrow pushing mechanism to show the formation of 2-pentyne from 2-butene. Use any…

A: First we convert but-1-ene from but-2-ene.. And then with the help of reagent we get pent-2-yne...

Q: Comparing two solutions: A. 1.0M Na3PO4 and B. pure water, which solution A or B has the greater…

A: We are given 1.0 M Na3PO4 solution and pure water. We need to compare boiling points of these two.

Q: 23. Treatment of 1,2-dimethylcyclopentene with OsO4, followed by aqueous NaHSO3, produces which of…

A: we have to predict the product of reaction of 1,2-dimethylcyclopentene with OsO4, NaHSO3

Q: DHE FOR (H14 is not on the chart Cakulat OHE OF GHiyle) slan 2H₁410+21₂ +4 (02_) 140 (0) SH₂=-8/35K)…

A: The balanced chemical reaction given is 2 C7H14 (l) + 21 O2 (g)→ 14 CO2 (g) + 14 H2O (l); ∆H°R =…

Q: of indiante which is the main product. Justify your answer. 6) present the possible mechanism for…

A: To answer: Indicate which is the main product. Justify your answer. Present the possible mechanism…

Q: (b) Carbon tetrachloride has a vapor pressure of 200 torr at 23 °C. This solvent can dissolve candle…

Q: What is the relationship between the two compounds shown below? Select one: a. enantiomers b.…

A: Disclaimer Since we are not providing any handwritten solution thank you. Therefore the solution has…

Q: where are each chemical component

A: Amines are Basic compounds and soluble in Inorganic acids like HCl. Carboxylic acids are soluble in…

Q: (b) The molar solubility of silver bromide is 7.1 x 107 mol L¹ at 25°C. Calculate the Ksp for silver…

A: We are given molar solubility (s) = 7.1×10–7 mol/L at 25°C we are to calculate the Ksp of AgBr at…

Q: Identify the important peaks in the following MS spectral data and draw the structure of the…

A: "Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: A 22.5 mL sample of 0.217 M diethylamine, (C₂H5)2NH, is titrated with 0.295 M hydrobromic acid.…

Q: A catalyst like chlorine gas that assists the breakdown of ozone can be described as a)…

Q: Methylamine, CH3NH2, is a weak base. In 0.200 M CH3NH2, only 8.4 % of the base has undergone…

Q: A. 2NO2(g) → N2O4(9) B. Fe(s) → Fe(1) C. 302(g) → 203(g) D. 12(g) → 12(s) E. 2Fe(s) + O2(g) →…

Q: What is the pH of a solution with a hydronium ion concentration of 3.9x10-7 Record to the tenth's…

Q: HC1 + (CH₂CH₂)₂0 CI + نے

Q: With the temperature at 2.40 × 10² °C and the partial pressures of the gases of PPC₁, = 0.233 bar,…

Q: Use the molecular orbital diagram shown to determine which of the following is paramagnetic.

Q: For the following compounds.... 1. Provide their molecular formula 2. Provide their IUPAC name 3.…

A: 1. The molecular formula of first compound : C7H12O as there as 7 carbons, 12 H and 1 O. The…

Q: The K₂ of a monoprotic weak acid is 0.00316 M. What is the percent ionization of a 0.150 M solution…

Q: Rank the following in order of acidity OH (!) () (least acidic) II<III<] (most acidic) (11) ОН NO…

A: Acidic nature of any compound depends on the ease of giving H+ ions when dissolved in water.

Q: Using the solubility curve above, how many grams of potassium iodide will dissolve in 100 grams of…

Q: CH3 CHCH CHBrCH2 C≡C CH(OH)CH2CH3 Need to draw this 3D structure w/ chiral centers and come up with…

A: Here we have to draw all possible 3D stereoisomers of the following given compound and to write…

Q: The preparations of two aqueous solutions are described in the table below. For each solution, write…

A: In the given question we have to write the chemical formula of the major species present at…

Q: 14. Design a synthesis for the following. Use any other reagents that you need. HO (H₂C)₂NH₂C

A: To get desired product, the following reactions are required. Oxidation : Alcohol to ketone Witting…

Q: Ethane HCI Br2 Uv H H2O Sulfuric OCH3 B 1 mol h2/ lindlars F Br2 D E 2NaNH2 NaNH2

Q: 2. Calculate the theoretical Amax the following compound.

Q: When a leaf of fresh sage or mint is rubbed between your hands, the fragrance is immediately…

A: Kinetic Molecular Theory is a set of postulates which describe the behavior and characteristics of…

Concept explainers

Alkanes and Cycloalkanes

Alkanes are saturated organic compounds which are made up of C and H atoms. Alkanes have the general formula of CnH2n+2. Alkane contains sp3 hybridized carbon atoms with four sigmas (σ) bonds & every hydrogen atom is connected with one of the carbon atoms. The size of the alkane could be determined by the number of carbon atoms located in it.

Question

13. How many possible stereoisomers are there for Crestor® (rosuvastatin), a medication used to reduce
cholesterol?
O
S
N
O
N.
N
MEM
Veg
a. 2
ن
نے
b. 4
c. 6
d. 8
OH OH
CO₂H

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Step by step

Solved in 2 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Indicate the relationship between each pair. Choose from: configurational stereoisomers,conformers, constitutional isomers, or different formulas (Each term is used at least twice.)
How many stereoisomers estuary for this molecule? Show how you know. A. 8 B. 3 C. 4 D. 6
Draw all possible constitutional isomers and stereoisomers for acompound of molecular formula C6H12 having a cyclobutane ring andtwo methyl groups as substituents. Label each compound as chiral orachiral.
Draw the three constitutional isomers having molecular formula C7H14 that contain a ve-membered ring and two methyl groups as substituents. For each constitutional isomer that can have cis and trans isomers, draw the two stereoisomers.
Why is this chair conformation the most stable trans-1-chloro-3-flurocyclohexane? Wouldn't the conformation with Cl & F in equatorial positions be the most stable conformation?
How many stereoisomers (count only carbon sp3 chiral centers) are there in cabergoline, a drug used to treat Parkinson's disease? A) 2 B) 4 C) 8 D) 16
a. Draw the 14 constitutional isomers of molecular formula C8H9Cl that contain a benzene ring.b. Name all compounds that contain a trisubstituted benzene ring.c. For which compound(s) are stereoisomers possible? Draw all possible stereoisomers.
a. Draw the 14 constitutional isomers of molecular formula C8H9Cl that contain a benzene ring. b.Name all compounds that contain a trisubstituted benzene ring. c.For which compound(s) are stereoisomers possible? Draw all possible stereoisomers.
What is the stereochemical configuration of the enantiomer of (2S, 4R)-2, 4-octanediol? (A diol is a compound with two â€”OH groups.)
Draw the most stable conformation of 1,4-dichlorobutane, using wedges and dashes to represent bonds coming out of the paper and going behind the paper, respectively.
cis-1, 2-Dimethylcyclobutane is less stable than its trans isomer, but cis-l, 3-dimethylcyclobutane is more stable than its trans isomer. Draw the most stable conformations of both, and explain.
up an example (not appearing in this ChemActivity) of a pair of molecules that are a)constitutional isomers, b) conformers. c) configurational stereoisomers.