13. Reflect and Apply Aspirin is an acid with a pK, of 3.5; its structure includes a carboxyl group. To be absorbed into the bloodstream, it must pass through the membrane lining the stomach and the small intestine. Electrically neutral molecules can pass through a mem- brane more easily than can charged molecules. Would you expect more aspirin to be absorbed in the stomach, where the pH of gas- tric juice is about 1, or in the small intestine, where the pH is about 6? Explain your answer.

13. Reflect and Apply Aspirin is an acid with a pK, of 3.5; its structure includes a carboxyl group. To be absorbed into the bloodstream, it must pass through the membrane lining the stomach and the small intestine. Electrically neutral molecules can pass through a mem- brane more easily than can charged molecules. Would you expect more aspirin to be absorbed in the stomach, where the pH of gas- tric juice is about 1, or in the small intestine, where the pH is about 6? Explain your answer.

Biochemistry

9th Edition

ISBN:9781305961135

Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal

Publisher:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal

Chapter2: Water: The Solvent For Biochemical Reactions

Section: Chapter Questions

Problem 21RE: REFLECT AND APPLY Aspirin is an acid with a pKa of 3.5; its structure includes a carboxyl group. To...

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REFLECT AND APPLY Aspirin is an acid with a pKa of 3.5; its structure includes a carboxyl group. To be absorbed into the bloodstream, it must pass through the membrane lining the stomach and the small intestine. Electrically neutral molecules can pass through a membrane more easily than can charged molecules. Would you expect more aspirin to be absorbed in the stomach, where the pH of gastric juice is about 1, or in the small intestine, where the pH is about 6? Explain your answer.
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