16.B. The formula for "Lubow's Solution" is as follows3: 1 g 500 mg Progesterone Hydrocortisone 2 g Propylene glycol Ethanol (95%) ad 100 mL (a) Calculate the quantities of each ingredient required to prepare 2.5 mL of solution. (b) How many milliliters of propylene glycol (sp. gr. 1.04) are needed to prepare a liter of the formula?
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- 3. Astelin nasal spray contains 0.1% azelastine hydrochloride and 400 µg/mL of benzalkonium chloride as a preservative. A container is capable of delivering 200 metered sprays of 0.137 mL each. The percent concentration of benzalkonium chloride in the preparation is ________ %, and this is equivalent to a ratio strength of 1:2500 w/v. True or False?A neonate patient weighing 3,821 grams is prescribed gentamicin 6 mg/kg in D5W for IV infusion. If the concentrated gentamicin injection contains gentamicin 10mg/mL, how many milliliters of gentamicin injection should be added to the dextrose? Round your answer to the nearest tenth of a milliliter.31. The formula for a cosmetic cream calls for 5% of an emulsifier blend consisting of Span 60 and Tween20. If the Required HLB of the oil phase is 14.0, how much of each of the emulsifiers, respectively, shouldbe used in preparing 500 grams of the cream? (HLB for Span 60 = 4.7; HLB for Tween 20 = 16.7)a. 5.6 grams; 19.4 gramsb. 8.4 grams; 16.6 gramsc. 12.5 grams; 12.5 gramsd. 15.2 grams; 9.8 grams
- A 5 ml vial of hydrocortisone is having 2% (w/v) concentration. How many vials will be required, if we need to prepare 30 ml of a 8 mg/ml oral hydrocortisone?The formula for a sports rub cream is given in the literature as follows:Methylsalicylate 15 mLMenthol 10 gEucalyptus oil 1 gHydrophilic ointment, q.s. ad 100 g If the specific gravity of methyl salicylate is 1.18, how many grams of methylsalicylate would be needed to prepare two dozen 30-g tubes of ointment?Propanamide and methyl acetate have about the same molar mass, both are quite soluble in water, and yet the boiling point of propanamide is 486 K, whereas that of methyl acetate is 330 K. Explain.
- Thimerosal Tincture USP contains 0.1% w/v thimerosal and 50% v/v ethyl alcohol. If the cap is left off of a 15-mL bottle of the tincture, and the ethyl alcohol evaporates leaving a final volume of 9.5 mL, what is the concentration of thimerosal in the evaporated solution expressed as a ratio strength?The concentration of alcohol 1CH3CH2OH2 in blood, calledthe “blood alcohol concentration” or BAC, is given in unitsof grams of alcohol per 100 mL of blood. The legal definitionof intoxication, in many states of the United States, is that theBAC is 0.08 or higher. What is the concentration of alcohol,in terms of molarity, in blood if the BAC is 0.08?At 39.9ºC, a solution of ethanol (XetOH = 0.9006, P * etOH = 130.4 Torr) and isooctane (P * iso = 43.9 Torr) forms a vapor phase with YetOH = 0.6667. The total pressure is 185.9 a. Calculate the activity and the activity coefficient of each component.b. Calculate the total pressure the solution would have if it were ideal.c. Comparing the ideal pressure to the actual pressure, what does this indicate about the molecular interactions?
- The prescriber ordered oxacillin 500mg IM q6h. The instructions on the 2g vial state to reconstitute the powder with "11.5mL of sterile water for injection, yielding 250mg/1.5mL" Whatis the strength of the reconstituted solution? How many milliliters would you administer?Rocephin (ceftriaxone sodium) 370 mg IM stat.The label on the ceftriaxone states to reconstitute the 1 g vial with 2.1 mL of sterile water for injection, which results in a strength of 405 mg/mL. How many milliliters will you administer?The principal component of many kidney stones is calcium oxalate, CaC2O4 . A kidney stone recovered from a typical patient contains 8.5 * 1020 formula units of calcium oxalate. How many moles of CaC2O4 are present in this kidney stone? What is the mass of the kidney stone in grams?