18. 2-Aminopyridine can be nitrated or sulfonated under much milder conditions than pyridine itself; substitution occurs chiefly at the 5-position. Account for these facts.

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter24: Amines And Heterocycles
Section24.SE: Something Extra
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18. 2-Aminopyridine can be nitrated or sulfonated under much milder
conditions than
pyridine itself; substitution occurs chiefly at the 5-position. Account
for these facts.
Transcribed Image Text:18. 2-Aminopyridine can be nitrated or sulfonated under much milder conditions than pyridine itself; substitution occurs chiefly at the 5-position. Account for these facts.
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