2 Propose a mechanism for copper mediated Chan-Lam coupling of aryl boronic acids and benzoic acids below B(OH)2 Cu(OTf)2, urea, E1OAC HO 60 °C, air

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter23: Amines
Section: Chapter Questions
Problem 23.26P: The pKa, of the conjugate acid of morpholine is 8.33. (a) Calculate the ratio of morpholine to...
icon
Related questions
icon
Concept explainers
Question
2.
2 Propose a mechanism for copper mediated Chan-Lam coupling of aryl boronic acids and benzoic acids below
B(OH)2
Cu(OTf)2, urea, EtOAc
HO
+
60 °C, air
Transcribed Image Text:2. 2 Propose a mechanism for copper mediated Chan-Lam coupling of aryl boronic acids and benzoic acids below B(OH)2 Cu(OTf)2, urea, EtOAc HO + 60 °C, air
Expert Solution
steps

Step by step

Solved in 2 steps with 1 images

Blurred answer
Knowledge Booster
Aromatic Compounds
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9781305580350
Author:
William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:
Cengage Learning