2. Explain what you understand by the term selectivity with respect to molecules binding to the active site of a receptor.

Q: Figure 2. The structure of the opioid binding receptor

A: Opioid receptor is a type of G protein coupled receptor which takes part in signal transduction. In…

Q: 1. What are the 3 important colligative properties discussed in class, give their applications.

A: Colligative properties are the properties of solutions that depends on the number of solute…

Q: (b) What is the binding site' of a receptor? How does the binding site change shape during…

A: In biochemistry the initiation of biological process is associated with the process of…

Q: 3. How does dimerization of a receptor tyrosine kinase promotes autophosphorylation of the…

A: The tyrosine kinase-associated receptors contain an N-terminal extracellular ligand-binding domain,…

Q: 1. If neither Viagra or ginseng works to fix the cat's problem,  what protein(s) would you suspect…

A: The nitric oxide (NO) is produced by the endothelial cells or by the neuronal cells. This NO diffuse…

Q: 3- Which is incorrect regarding ligand-protein binding reactions? a. Allosteric modulation of the…

A: The ligand-protein binding reaction is a type of reaction that involves conformational changes to…

Q: 5. Why does the blood-brain barrier prevent entry of drugs into the brain? What physicochemical…

A: Drug delivery to the brain is the way toward passing remedially dynamic molecules over the…

Q: From what you have learned in Biology, why is membrane potential essential among plants and animals?

A: Membrane potential is the potential gradient which is created due to difference in electric…

Q: How is it verified that the Lc chain formed is functional? a. translation is carried out b. the…

A: Immunoglobulin light chains refer to the two polypeptide chains or subunits of an antibody. The…

Q: Why do receptors have carbohydrates in their structures where it Functions as binding sites for…

A: Glucose is a monosaccharide and it is a simple sugar that is the most important source of…

Q: 1. Which amino acids would most likely be found in the transmembrane spanning region of an integral…

A: Amino acids are the constituents or sub units of protein molecules. There are two functional groups…

Q: n the discovery of new drugs, the chemical and physical properties of a molecule are very important…

A: Hi! Thanks for your question. As you have posted multiple questions and have not mentioned which one…

Q: iii) Two of the regulatory networks (1-4) shown below are consistent with the results presented…

A: Gene expression is predominantly regulated at the transcriptional level, owing to protein binding to…

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A: Kidney plays an important role in maintaining the osmoregularity of the body or more precisely…

Q: 9. Proteins A and B bind ligand C. Protein A binds C with a K, of 2 x 105 M-1. Protein B binds C…

A: Binding affinity is the strength of the binding interaction between a single biomolecule (protein or…

Q: 19- Which statement is true for ion channel? a) There is no selectivity based on the diameter of ion…

A: First we will learn about ion chanells. The ion chanells are the membrane proteins which allows ions…

Q: 3. Below is a small peptide. What fumotional group or region of the peptide will allow you to…

A: Ultraviolet-visible (UV-Vis) spectrophotometry is an instrument widely used in biochemistry to…

Q: 3. When you think about the primary structure of the mannose-6-P receptor, assuming that it is an…

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Q: 15. Shown here is a 5HT3 receptor protein, what structural motif is exhibited in the alpha domain.…

A: There are different macromolecules present in the living organism. They include carbohydrates,…

Q: Describe the three domains of a receptor tyrosine kinase. Explain the structure of the…

A: Receptor Tyrosine kinase are the most effective high affinity cell surface receptors that acts for a…

Q: Hydrophobic signal molecules typically ...     a)  bind to receptor proteins in the cytosol.   b)…

A: Introduction :- Signal transduction is the process through which a cell receives signals from the…

Q: When somebody experiences frequent vomiting, one possible side effect is that their blood pH can be…

A: Introduction: Vomiting is the involuntary action, which results in expelling the content of the…

Q: 2.) Give one example of a trans-acting regulatory protein.

A: In context of transcription, a trans-acting element is usually a DNA sequence that contains a gene.…

Q: 8. You are testing a drug that is an allosteric regulator of PFK-1 and get the following data. Is…

A: As there are many questions given in one, solution is provided only to the first question (question…

Q: Speculate on what the receptor sites for each of these molecules might be in terms of shape and…

A: Receptors are membrane proteins consisting of proteins, and glycans. Its extracellular domain…

Q: 1. The four steps in the signal transduction pathway are listed below, a-d. Label the diagram above…

A: 1. Signal transduction also known as cell signaling is a pathway which involves the transmission of…

Q: Hydrophobic signal molecules typically . a) bind to receptor proteins in the cytosol. O b) bind to…

A: 1st answer is (e) 2nd answer is (e)

Q: Suppose you want to develop a drug that targets nuclear receptors. What chemical characteristic of…

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Q: Describe how studying 3-D structures of PTGS1 and PTGS2 could help researchers design a drug that…

A: Proteins are unbranched polymers constructed from 22 standard α-amino acids. They have four…

Q: Please describe the function of true activators? Please discuss the effect of ligand binding on the…

A: A true activator is a protein, which is also known as a transcription factor. The true activators…

Q: What amino acid residues interact with methylphenidate in DAT and NET protein active sites? please…

A: DAT and NET proteins are  Dopamine Transporter and NET is Nor-Epinephrine Transporter proteins, both…

Q: In an NMR experiment, if a ligand is added to a protein and formed a ligand-protein complex, almost…

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Q: Many types of protein–glycan interactions are low affinity, and in some cases high avidity is…

A: When it comes to biomolecular interactions, avidity refers to the sum of the strengths of several…

Q: For a binding protein to show positive cooperativity…. Choice 1 of 4:the protein must be able to…

A: Positive cooperativity is a phenomenon which shows positive binding of one or more ligand to a…

Q: 3) What specific proteins might be targeted for up- or downregulated adsorption when designing an…

A: Biological implantation can be simply described as replacement of a biological tissue by…

Q: 1. What is one advantage of signal transduction being a pathway (several steps)?

A: Signal transduction is the process by which a chemical or physical signal is sent across the cell as…

Q: What is the role of ATP in cell signaling in biochemistry?

A: ATP has key functions in cell signaling and the signal transduction process heavily relies on ATP.…

Q: 1. Which of the following types of proteins defend the body against infectious agents? a. receptors…

A: proteins are body's building blocks that have multiple functions, such as, structure building,…

Q: Explain what you understand by the term 'selectivity' with the respect to molecules binding to the…

A: A receptor is a protein molecule that binds to its specific ligand. The receptor molecules generally…

Q: Search for the `P06858` a) Give information about the PTM and Processing of

A: triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and…

Q: 9. Shown below is a binding pocket for a protein with a ligand bound. The ligand interacts with a…

A: For an equilibrium interaction between a Protein 'P' and Ligand 'L'  forming a Protein-Ligand…

Q: 98. The correct sequence of cell signaling is

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Q: 3.Cell surface receptors used in cell signalling are usually proteins that extene of the membrane to…

A: The extracellular matrix (ECM) is a non-cellular portion that serves as a structural scaffold for…

Q: Many proteins on the outer surface of the cell are receptors, sites that “recognize” and bind with…

A: The thin, living, elastic, semi permeable membrane that is present around the cell is called cell…

Q: GABA receptors play an essential role in neurotransmission in the central nervous system. In…

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Q: The dissociation constant (Kd) of a receptor is:  BIOCHEMISTRY basic  the concentration of a…

A: “Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: 2. The percentage of transmittance of a solution of X at 300 nm and 25 C is 20% for a 5x104 M…

A: In biochemistry, through Beer-Lambert Law either the absorbance, molar absorptivity, length of the…

Q: Type of receptor in cancer disease 2. Signal mechanism in cancer (what us the ligand in cancer…

A: Cancer is an abnormal and unregulated proliferation of cells. In a few cases, this uncontrolled cell…

Q: 3) The "Met" receptor is a membrane receptor protein responsible for initiating signal transduction…

A: The matured Met receptor is functioning when it becomes located at the plasma membrane and can be…