24. Pig liver esterase (PLE) is an enzyme that is used hydrolyze esters. In the to stereoselectively following reaction, only one enantiomer of starting material reacts with PLE. The (1R, 2R)-1,2- cyclohexanediol product has a specific rotation of - 39°, and the reaction proceeds with a 94% ee. (i) Calculate the percent of each enantiomer present. (ii) Calculate the specific rotation of the mixture. + PLE (racemic mixture) A) (i) 94% and 6%, (ii) [a] = -33° B) (i) 98% and 2%, (ii) [a] =-37° C) (i) 97% and 3%, (ii) [a] = -37° D) (i) 97% and 3%, (ii) [a] = -241° E) (i) 94% and 6%, (ii) [a] = -241° OH OH

24. Pig liver esterase (PLE) is an enzyme that is used hydrolyze esters. In the to stereoselectively following reaction, only one enantiomer of starting material reacts with PLE. The (1R, 2R)-1,2- cyclohexanediol product has a specific rotation of - 39°, and the reaction proceeds with a 94% ee. (i) Calculate the percent of each enantiomer present. (ii) Calculate the specific rotation of the mixture. + PLE (racemic mixture) A) (i) 94% and 6%, (ii) [a] = -33° B) (i) 98% and 2%, (ii) [a] =-37° C) (i) 97% and 3%, (ii) [a] = -37° D) (i) 97% and 3%, (ii) [a] = -241° E) (i) 94% and 6%, (ii) [a] = -241° OH OH

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter24: Amines And Heterocycles

Section24.9: Heterocyclic Amines

Problem 24P

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