asap please. 3. After an IV bolus dose of 500 mg of a drug, the following data were collected:(first order elimination)Time (hrs)Cp (mcg/ml)1642 3 44834Determine the following:a) Cob) Rate constantc) Half-lifed) Total area under the curve8761025 14 7.8 4.2Please solve using these equations:dCp/dt=-k(Cp)t1/2= 0.693/kCp=C0e^-k(t)

We have to determine C0 , Rate constant (k) and Half life (t1/2) of the given I order reaction.…

3. After an IV bolus dose of 500 mg of a drug, the following data were collected: (first order elimination) Time (hrs) Cp (mcg/ml) 1 64 2 48 Determine the following: a) Co b) Rate constant Half-life 3 34 4 25 6 14 8 7.8 10 4.2

3. After an IV bolus dose of 500 mg of a drug, the following data were collected: (first order elimination) Time (hrs) Cp (mcg/ml) 1 64 2 48 Determine the following: a) Co b) Rate constant Half-life 3 34 4 25 6 14 8 7.8 10 4.2

Fundamentals Of Analytical Chemistry

9th Edition

ISBN:9781285640686

Author:Skoog

Publisher:Skoog

Chapter30: Kinetic Methods Of Analysis

Section: Chapter Questions

Problem 30.1QAP

See similar textbooks

Related questions

Q: The absorption spectrum of the complex ion [Co(NH3)6]3+ has strongly absorbs blue light at a…

Q: The vapor pressure of Substance X is measured at several temperatures: temperature vapor pressure…

Q: How many molecules are in each sample? 69.0 g N2 (Express your answer using three significant…

A: Mole can be defined as a standard unit for measuring large quantities of very small entities such as…

Q: what intermolecular force is this

A: The forces acting between two atoms or molecules are called intermolecular forces.

Q: MISSED THIS? Read Section 3.9. You can click on the Review link to access the section in your e…

A: The percent mass of an element in a compound can be calculated by using the following formula:…

Q: The names is INCORRECT. Write and draw the most probable IUPAC name.

Q: How many non-equivalent ("different" kinds of) protons are there in this compound? H₂C CH3 Br

Q: Which of the following represents an exact quantity? A) There are 2.54 cm in an inch. B) A man is 5…

A: Concept based on the exact numbers and measured numbers.

Q: A student ran the following reaction in the laboratory at 298 K: 2NO(g) + Br₂ (9) ⇒ 2NOBr(g) When…

Q: What do you notice when you compare the initial boiling temperature for the 2 concentratraction

A: Boiling Point Boiling point of any solution will always be greater than the pure solvent (water that…

Q: Which statement about atoms is correct? A. Atoms are not composed of smaller particles. OB. Each…

A: In atom, there is nucleus (protons and neutrons) and electrons are revolving around the nucleus.

Q: Three bottles of aqueous solutions are discovered in an abandoned lab. The solutions are green,…

A: [Cr(H2O)6]3+ is green in colour since H2O is weak ligand hence ∆° is small, [Cr(NH3)6]3+ is yellow…

Q: Calculate the number of grams of sodium in 2.20 g of this sodium-containing food additive.…

A: Given, mass of sodium benzoate (NaC7H5O2) = 2.20 g mass of sodium (Na) = ? Note: molar mass of…

Q: H3C-C C-H + H₂O 1 M HNO3 H₂C=CH₂ OH H₂C-CH3 --Ch explain why the following reaction would not work…

A: HNO3 is a powerful oxidising agent so it oxidises alkenes to the carboxylic acid not to the ketone.

Q: ▼ Part A How many neutrons are found in one atom of 38 Ar? Express your answer numerically. View…

A: Atom consist of protons,neutrons and electrons.Protons and neutrons are present in nucleus of an…

Q: 20. Some alcohols undergo rearrangement or other unwanted side reactions when they dehydrate in…

A: Alcohols undergo dehydration in the presence of POCl3 and Pyridine to form an alkene. POCl3 reacts…

Q: Calculate the wavelength of light (in nm) of light that has a frequency of 1.00 x 10¹5 Hz. 30.0 nm…

A: Given, Frequency (f) = 1.00 × 1015 Hz = 1.00 × 1015 s-1 Wavelength (λ) = ? nm Note: Speed of light…

Q: Give the formal charge on the highlighted carbon in each species. All H’s and electrons on the…

A: Formal charge is theoretical charge over an individual atom of polyatomic molecule. Formal charge is…

Q: An unknown compound contains only carbon, hydrogen, and oxygen (CxHyOzCxHyOz). Combustion of 5.00 gg…

Q: Does increasing the total energy of the system make the atoms more or less likely to stick together?…

A: We have to tell about stability of molecule with regarding the energy.

Q: mole sample of ammonia at 14.0 atm and 25 °C in a cylinder fitted with a movable piston expands…

A: We know according to ideal gas equation PV = nRT P is the pressure in atm V is volume in L n is…

Q: A 47.8-mg sample of boron reacts with oxygen to form 154 mg of the compound boron oxide. What is the…

A: Given, Mass of boron (B) = 47.8 mg = 0.0478 g Mass of boron oxide formed = 154 mg = 0.154 g…

Q: Practice: Which molecules could have additional resonance forms? Circle 2 c Practice: Circle which…

A: In chemistry, resonance also called mesomerism ,is a way of describing bonding in certain molecules…

Q: Both of the OF2 and CS2 molecules contain polar bonds. Explain why one of these molecules is polar…

A: Given: Both of the OF2 and CS2 molecules contain polar bonds. We have to find why one of these…

Q: Draw all 5 Bond line structures for Collin on a hexagonal grid?

A: BOND LINE STRUCTURE:- Structure of organic compounds in which bond between to atom is represented by…

Q: Show solution on how many milligrams there are in 25 nanograms

A: Given -> 25 nanogram

Q: The rate law for the reaction 3A+2B+2C-D is rate = K[A]¹[B][C]¹ What is the overall reaction order?…

Q: The wavelength for the color indigo is 445 nanometers (nm). What is this wavelength in kilometers…

Q: A 0.1860 g rock sample containing an unknown amount of Ca was dissolved in HCI and diluted to 100.0…

A: We have to draw the concentration of the standard solution versus emission intensity plot to find…

Q: 1. Consider the reaction CO(g) +H2O(g) = CO2(g) +H2(g) Kc=102Kc=102 at 500 KK A reaction mixture…

Q: When solutions of Pb2+ and CrO42-are mixed the precipitate PbCrO4 is produced. What volume of 0.1750…

A: The needed balanced chemical equation for the above precipitation reaction is, Pb2+ + CrO42- →PbCrO4…

Q: (16) The constant pressure molar heat capacity of nitrogen is given by the expression: Cmp (27 +5.9…

Q: Part A When ethanol (C₂H₂O(aq)) is consumed it reacts with oxygen gas (O₂) in the body to produce…

A: Combustion reactions are those reactions in which a substance reacts with oxygen gas and release…

Q: rect IUPAC name for the con

A: IUPAC nomenclature is used for naming the organic compounds as recommended by international Union of…

Q: In the proton NMR, the hydrogens on the carbon next to the benzene ring, labeled J, would appear as…

A: Multiplicity :

Q: For the following reaction at equilibrium CO(g) + 2H2(g) CH3OH (g) In a 2.00 L flask, a mixture of…

Q: CI O

Q: What is the mass in grams of 68.3 mol Xe?

A: Mole can be defined as a standard unit for measuring large quantities of very small entities such as…

Q: For the reaction: 2CO2 (g) = 2CO(g) + O2(g), What can be said about this reaction at this…

Q: 5. Solvolysis of bromomethylcyclopentane in methanol gives a complex product mixture of the…

Q: 50.0 g of N2O4 is introduced into an evacuated 2.00 L vessel and allowed to come to equilibrium with…

A: mass of N2O4 = 50.0 g molar mass of N2O4 = 92.0 g/mol moles of N2O4 = 50.0 g /92.0 g/mol = 0.543…

Q: How much money will it cost you to drive 106.0 miles if your hybrid gets 46.0 miles per gallon and…

Q: How many non-equivalent ("different" kinds of) protons are there in this compound? CH3 Br CH 3

Q: Gaseous ethane (CH3 CH3) will react with gaseous oxygen (O₂) to produce gaseous carbon dioxide (CO₂)…

Q: what is the chemical formula for potassium phosphate?

A: what is the chemical formula for potassium phosphate?

Q: FALLINGBAL Give the combination formulas with the explanation for a compound containing C, H, O…

A: Spectroscopic techniques (data) are used to find out structure of chemical compound.

Q: V Convert the following measurement. 0.0044 1-02

Q: of 15 Macmillan Learning > Enter the formula for each ionic compound. manganese(II) chloride: MnCl₂…

A: The formula of given compound can be given by:

Q: Give the systematic names of these compounds. Spelling counts. Cul(s): Fe₂O3(s): CoF₂ (s): FeO(s):…

Q: A gas whose Cv=1.386 kJ/kg.K and R= 0.485 kJ/Kg.K Determine the MW in kg/kgmol.

Question

asap please.

3. After an IV bolus dose of 500 mg of a drug, the following data were collected:
(first order elimination)
Time (hrs)
Cp (mcg/ml)
1
64
2 3 4
48
34
Determine the following:
a) Co
b) Rate constant
c) Half-life
d) Total area under the curve
87
6
10
25 14 7.8 4.2
Please solve using these equations:
dCp/dt=-k(Cp)
t1/2= 0.693/k
Cp=C0e^-k(t)

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1

Step 2

Step 3

Step 4

Step by step

Solved in 4 steps with 2 images

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

The color change accompanying the reaction of phenolphthalein with strong base is illustrated below. The change in concentration of the dye can be followed by spectrophotometry (Section 4.9), and some data collected by that approach are given below. The initial concentrations were [phenolphthalein] = 0.0050 mol/L and [OH] = 0.61 mol/L. (Data are taken from review materials for kinetics at chemed.chem.purdue.edu.) (For more details on this reaction see L Nicholson, Journal of Chemical Education, Vol. 66, p. 725, 1989.) (a) Plot the data above as [phenolphthalein] versus time, and determine the average rate from t = 0 to t = 15 seconds and from t = 100 seconds to t = 125 seconds. Does the rate change? If so, why? (b) Use a graphical method to determine the order of the reaction with respect to phenolphthalein. Write the rate law, and determine the rate constant. (c) What is the half-life for the reaction?
The company performs accelerated ageing studies in which a suspension of D is stored at different temperatures. They obtain the degradation rate constants in the table below. Calculate the rate constant for degradation at 25 ºC. (45 % of marks) T / ºC k / d-1 40 0.28 50 0.56
Chlorine is commonly used to disinfect drinking water,and inactivation of pathogens by chlorine follows first-orderkinetics. The data in figure show E. coliinactivation (a) Determine the first-order inactivation constant, k. (b) How much contact time is required for 95% inactivation?
( plz asap within 10 min dont ans after 11.28 ...if late than this dislike
Given the following data, graph the data for the Poliomyelitis virus, using hypobromite as a disinfectant. Determine the inactivation constant and the time required for 99.99 percent (4 log removals) inactivation of this virus. The concentration of hypobromite is 0.1 mg/L.Time (s) N (# organisms/L)0.0 1,0002.0 3504.0 786.0 208.0 610.0 212.0 1
A river water sample of 25°C is contaminated with diazepam with initial concentration of 5000 ppb (or ng/L) when it secondary biodegradation rate in water, Kd = 10^1.3 (cu cm/mol-sec) at 25°C and molar mass of diazepam is 284.7g/mol. What is the half life of the diazepam in hours? Note: I need right answer with clear calculations.
Use the data in Figure 14.2 to calculate the average rate ofappearance of B over the time interval from 0 s to 40 s.
Aspirin sample solutions were stored at 30°C and were assayed every month for six months. The equation obtained from its kinetic profile was y = -0.0033x - 1.004. a. What is the rate constant of aspirin at 30°C? b. Calculate the half-life of aspirin in months. c. Calculate the shelf-life of aspirin in years
The first-order degradation rate constant k was determined to be 0.0125/day for contaminant A and 0.0030/day for contaminant B in a soil. Calculate the half-life T1/2 and the 95% dissipation time for these contaminants in the soil. Compare the persistence between the two contaminants.
What is the enzymatic rate given two sets of data points: 120s, 118kPa and 90.0 s, 112 kPa
If a mixture was prepared by diluting 7.0 mL of the Blue#1 solution with water to a final volume of 10.0 mL and mixing this with 2.0 mL of diluted bleach how many seconds would it require for the mixture to have an absorbance of 0.120? Use your measured values of b and of the average rate constant, k’ to answer this question. Show all work. Pls help me out asap!!
In a study of the gas phase decomposition of sulfuryl chloride at 600 KSO2Cl2(g)SO2(g) + Cl2(g)the concentration of SO2Cl2 was followed as a function of time.It was found that a graph of ln[SO2Cl2] versus time in minutes gave a straight line with a slope of -4.34×10-3 min-1 and a y-intercept of -5.20 .Based on this plot, the reaction is _______zerofirstsecond order in SO2Cl2 and the rate constant for the reaction is min-1.