3. At which step would a mutation lead directly to the formation of an altered gene? DNA is copied and each new cell gets a full copy. Step A a. А b. B с. С d. D Information oopied from DNA
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- Predict the resulting DNA strand in the presence of a mutagen that causes the ADDITION of one Cytosine in the N-terminal of DNA----TAG TAC TAG T --Normal DNA strand TAG TAG TAT C TAG TAT CAG T CTA TAC TAG T TAG TAG AGC TDuring transformation a cell usually incorporates only one or afew fragments of DNA. Explain.Our bodies are not defenseless against mutagens that alter our genomic DNA sequences. What mechanisms are used to repair DNA?
- Energy that drives the attachment of a nucleotide to the end of a growing strand of DNA comes from ______. a. phosphate-group transfers from ATP b. DNA polymerase c. the nucleotide itself d. a and cWhich of the following statements describe reversal of DNA repair mechanism. A. UV light blocks the translation of mRNA beyond the damaged area B. Reversal of DNA repair mechanism requires a DNA template C. UV light is needed to initiate the formation of pyrimidine dimers D. None of the statement is correctWhich of the following is not a factor that increases mutations? a. Fast rates of replication b. Ionizing radiation c. Repair enzymes d. UV radiation e. Replication error
- Which statement regarding transitions and transversions is TRUE? a) An adenine to guanine change is a transversion b) Transversions are more commonly found in nature that are transitions c) A cytosine to guanine change is a transition d) Transversions cause a distortion in the DNA double helixWhich of the following is/are associated with spontaneous mutation?a. An occurrence of lung cancer due to smokingb. A nonsense mutation in an exon caused by an errorin DNA replicationc. An indel mutation in an intron caused by replicationslippaged. A nonsense mutation in an exon caused by an errorin DNA replication, and an indel mutation in an introncaused by replication slippageOne of the mechanisms that leads to the DNA mutations is a process known as DNA polymerase slippage which occurs during DNA replication. Which of the following statements about DNA polymerase slippage is correct? A. Backward slippage in the newly synthesized strand will lead to an insertion mutation. B. DNA polymerase slippage can lead to a point or substitution mutation. C. Forward slippage in the template strand will lead to an insertion mutation. D. All of the above
- Cells have only one fundamental wayof replicating DNA but many differentways of repairing it. Are there stillother, undiscovered ways that cellshave for repairing DNA?A mutation in which of these proteins will lead to increased mutations in all daughter cells? A. helicase B. topoisomerase C. ligase D. DNA polymeraseWhich of the following is not a necessary component for DNA synthesis? a. DNA polymerase I b. dNTPs c. Copper ions d. Parental strand of DNA e. All of the above are required for DNA synthesis