3. Oxazolidines are important synthetic precursors for the production of drugs. The reason is that these derivatives prevent bacteria from producing the proteins they need to grow and multiply, examples are linezolid and tedizolid. One of the reactions through which the derivatives are obtained is by addition processes. An example is shown below, in which oxazolidine is treated with diethylzinc, obtaining intermediate B, which facilitates the continuation of the reaction. Upon continuation of the process, an addition to carbonyl group is carried out to obtain compound C. Complete the synthesis route steps with the correct compounds. EtzZn aire CH2CI2 aire CH2CI2
3. Oxazolidines are important synthetic precursors for the production of drugs. The reason is that these derivatives prevent bacteria from producing the proteins they need to grow and multiply, examples are linezolid and tedizolid. One of the reactions through which the derivatives are obtained is by addition processes. An example is shown below, in which oxazolidine is treated with diethylzinc, obtaining intermediate B, which facilitates the continuation of the reaction. Upon continuation of the process, an addition to carbonyl group is carried out to obtain compound C. Complete the synthesis route steps with the correct compounds. EtzZn aire CH2CI2 aire CH2CI2
Chapter19: Aldehydes And Ketones: Nucleophilic Addition Reactions
Section19.SE: Something Extra
Problem 50MP
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