3.Tay Sachs is a lysosomal storage disease that is inherited in an autosomal recessive manner (T= dominant allele; t = recessive allele). Individuals with Tay Sachs have a defect in the gene encoding hexosaminidase A, a lysosomal enzyme that breaks down cell membrane components called gangliosides. The inability to break down gangliosides causes harmful quantities of this lipid to accumulate in nerve cells of the brain, eventually leading to premature death of affected cells. There is no known cure for the disease, and death usually occurs by age 4. Jack and Jill have a child who has Tay-Sachs. What do you know about the genotypes of Jack and Jill? A.has the genotype DD B.has the genotype Dd C.is still of unknown genotype since there were offspring of both deaf and hearing phenotypes. D.has the genotype dd

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter21: Microevolution: Genetic Changes Within Populations
Section: Chapter Questions
Problem 12TYK: Discuss Concepts Many human diseases are caused by recessive alleles that are not expressed in...
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3.Tay Sachs is a lysosomal storage disease that is inherited in an autosomal recessive manner (T= dominant allele; t = recessive allele). Individuals with Tay Sachs have a defect in the gene encoding hexosaminidase A, a lysosomal enzyme that breaks down cell membrane components called gangliosides. The inability to break down gangliosides causes harmful quantities of this lipid to accumulate in nerve cells of the brain, eventually leading to premature death of affected cells. There is no known cure for the disease, and death usually occurs by age 4. Jack and Jill have a child who has Tay-Sachs. What do you know about the genotypes of Jack and Jill? A.has the genotype DD B.has the genotype Dd C.is still of unknown genotype since there were offspring of both deaf and hearing phenotypes. D.has the genotype dd
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