300 mg/di was revealed. Why was this accompanied by considerable increasing ammonia salts excretion till 10 g/day (0,5 g/day in norm)? For the answer: a) list pathways of ammonia detoxification in different tissues (brain, muscles, and liver), present appropriate reactions; b) specify amino acid which transports ammonia from muscles to kidney, present the reaction of its synthesis, point out enzyme; c) give the scheme of process accelerating in acidosis in the kidncy, specify its importance, point out enzyme the synthesis of which is induced under these circumstances; d) write down the formulae of salts in the composition of which ammonia is excreted in ketonemia.

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter19: The Peripheral Endocrine Glands
Section: Chapter Questions
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5. In the examination of diabetes mellitus patient the elevated ketone bodies level till
300 mg/dl was revealed. Why was this accompanied by considerable increasing
ammonia salts excretion till 10 g/day (0,5 g/day in norm)? For the answer:
a) list pathways of ammonia detoxification in different tissues (brain, muscles,
and liver), present appropriate reactions;
b) specify amino acid which transports ammonia from muscles to kidney,
present the reaction of its synthesis, point out enzyme;
c) give the scheme of process accelerating in acidosis in the kidney, specify its
importance, point out enzyme the synthesis of which is induced under these
circumstances;
d) write down the formulac of salts in the composition of which ammonia is
excreted in ketonemia.
Transcribed Image Text:5. In the examination of diabetes mellitus patient the elevated ketone bodies level till 300 mg/dl was revealed. Why was this accompanied by considerable increasing ammonia salts excretion till 10 g/day (0,5 g/day in norm)? For the answer: a) list pathways of ammonia detoxification in different tissues (brain, muscles, and liver), present appropriate reactions; b) specify amino acid which transports ammonia from muscles to kidney, present the reaction of its synthesis, point out enzyme; c) give the scheme of process accelerating in acidosis in the kidney, specify its importance, point out enzyme the synthesis of which is induced under these circumstances; d) write down the formulac of salts in the composition of which ammonia is excreted in ketonemia.
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