What is the major tissue source of Alanine Aminotransferase? 2. What is the clinical significance of elevated serum Alanine aminotransferase?
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1. What is the major tissue source of Alanine Aminotransferase?
2. What is the clinical significance of elevated serum Alanine aminotransferase?
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- 1. What is the optimum pH and temperature for salivary amylase?1. Explain the formation of thioether-linked prenyl anchor proteins and also explain the structure of caveolae.In many individuals with severe cases of A1AT deficiency (the ZZ genotype), intracellular accumulations in the liver are usually noted upon biopsy. What might be the cause of this phenomenon?
- explain the phenylketonuria disease mechanism1. State the functions of the different fat-soluble vitamins2. Define prostaglandins give their biological functions3. Define leukotrienes and give their biological functions7. People who have their gall bladder removed often lose weight and are advised to take supplements of the fat-soluble vitamins (A, D, E, K) to ensure they are getting enough of these vitamins. Explain the weight loss and why these vitamins are specifically targeted.
- People with lactose intolerance cannot digest the common dairy sugar lactose. Besides being careful not to eat dairy foods, is there anything else a lactose-intolerant person can do?Dysregulation of glutamate dehydrogenase (GDH), an enzyme that catalyzes the oxidative deamination of glutamate, leads to a variety of metabolic and neurological disorders. One such disorder is hyperinsulinism/hyperammonemia syndrome. 1. Describe the role of GDH including the structure, function and biochemistry of the protein and its contribution to the disease. 2. Discuss the several ways that this disease can be diagnosed in the lab 3. Discuss the mechanism by which pharmacological agents act to help in the management of the disease.17. Which statement about lipoproteins is TRUE? a high-density lipoproteins transport cholesterol from the liver to the cells b lipoproteins can transport fats from storage sites to sites where they are used c the liver is solely responsible for the synthesis of lipoproteins d very-low-density lipoproteins transport cholesterol from cells to the liver e increasing lipid (fat) content of a lipoprotein would increase its density
- What is application of D_serine?1- Which one of the following statements describes non - essential amino acids ? a) They can be synthesized from essential amino acids . b) They are ingested but not used in protein synthesis . c) They are stored in adequate amounts so are not needed in the diet . d) They are less important in cells than essential amino acids . 2- Some proteins contain additional amino acids that arise by modification of an amino acid already present in a peptide , examples include: a) Gamma Amino Butyric Acid. b) 5 - hydroxy Lysine c) 4 - hydroxy proline d) All of the above e) None of the aboveIs there a difference between the effects of sugar concentrations on protein denaturation? Why?
