A. Analyze the pedigree below and determine if the trait is inherited as autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, or Y-linked. Remember, data from human families is limited, so you may be unable to determine the inheritance with certainty. The key is that you justify your answer using data from the pedigree. 2 4 0-4
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- 1. Construct a pedigree chart of the trait traced in the situation below.2. The pedigree chart must be constructed with the names and genotypes at the bottom of every individual in the chart.If it is autosomal: Always use the first letter of the dominant trait to represent the dominant allele. For example, if the dominant trait is red, so the allele R-red, while r-yellow. For example, if the person is homozygous dominant for curly hair, we write CC as his genotype. If sex-linked, do not forget to write the parents’ chromosomes (XX-female, XY-male), with their corresponding superscripts (dominant or recessive). The superscript must be based on the first letter of the disorder. For example, the mother is a carrier of hemophilia (which is x-linked recessive), so we write XHXh. If the father has hemophilia, we write XhY. Put the pedigree chart using code properly. The situation is given below: Trait: NeurofibromatosisThe dominant form is neurofibromatosis, caused by the production of…1. Use the diagram of the pedigree above, which shows inheritance of an x-linked recessive trait through a family. Select ALL of the individuals in the pedigree who must be carriers for the trait. E G B C H A4) A testcross is used to determine which of the following? a) The phenotype of an individual with a dominant genotype b) The phenotype of an individual with a recessive genotype c)The genotype of an individual with a dominant phenotype d) The genotype of an individual with a recessive phenotype
- Examine the following pedigrees. Which is the most likely mode of inheritance of each disorder? (a) autosomal recessive (b) autosomal dominant (c) X-linked recessive (d) a, b, or c (e) a or c 10.1. Make a diagram / illustrate and explain the sample study of Mendel to show the occurrence of the following: a. incomplete dominance b. overdominance c. co-dominance3) A. How are the following proteins involved in cell division: condensing, cohesin, kinetochore complex, tubulin? B. Why does phenotype not always reveal genotype? C. How can Mendel's postulates of segregation and independent assortment be explained by meiosis? D. Explain the genotypic and phenotypic ratios predicted when performing a monohybrid and a dihybrid cross of heterozygotes? E. How can you use the product rule and sum rule to calculate the probability of a particular genotype resulting from crossing parents of specific genotypes?
- 3. A couple just had a baby, who has type-O blood. Upon learning the baby’s blood type, the father becomesinfuriated and accuses the mother of cheating on him. The mother has type-A blood and the father has type-Bblood. Knowing that the allele for type-O is recessive, answer the following questions.a. What is the relationship between the IA, IB, and i alleles?b. Is the father right? Or is he falsely accusing the mother? Explain. Include the genotypes of the parentsand the genotypes of their potential children.1. Huntington’s disease is a dominant trait inheritance in humans. What is/are the possible genotype/s of the mother if her husband does not exhibit the disease, but their children unfortunately got the disease? A. hh only B. HH only C. HH or Hh D. Hh only 2. Huntington’s disease is a dominant trait inheritance in humans. What is/are the possible genotype/s of the children if both parents do not exhibit Huntington’s disease? A. Hh only B. hh only C. HH or Hh D. HH only 3. Huntington’s disease is a dominant trait inheritance in humans. What is the probability of having a normal child if the mother does not have the disease while her husband has the disease? A. 0% or 50% B. 100% C. 25% D. 0% or 25% E. 50% 4. Huntington’s disease is a dominant trait inheritance in humans. What is the probability of having a girl child with Huntington’s disease if both mother and father has the heterozygous genotype for the disease? A. 0% B. 50% C. 75%…1. Incomplete dominance governs the pigment gene of a flower. A mating between heterozygotes yields the following phenotypic ratio: 10 yellow flowers, 35 pink flowers and white flowers. Which statement describes the situation? a. The flower pigment gene is defined by a pink and yellow allele. b. The heterozygotes were yellow. c. The heterozygotes were white. d. The flower pigment gene is defined by a red and a white allele. 2. Mendel's rules do not correctly predict patterns of inheritance for tightly linked genes or the inheritance of alleles that show incomplete dominance. Does this mean that his hypotheses are incorrect? A. Yes, because they are relevant to only a small number of organisms and traits. b. Yes, because not all data support his hypotheses. c. No, because he was not aware of meiosis or the chromosome theory of inheritance. d. No, it just means that his hypotheses are limited to certain conditions. 3. Discuss the inheritance of hemophilia
- 2. You cross a pure-breeding red guinea pig with short hair and a pure-breeding white guinea pig with long hair. Allof the offspring are long hair and cream colored.a. What type of inheritance is hair length? Hair color? How do you know?b. What are the genotypes of the parents?c. Determine the genotypes and phenotypes and how many are expected for the F2 generation. (Just leaveyour answers as a list with numbers beside them. No ratios required.)13. A dominant x-linked allele (B) gives normal color vision but the recessive allele (b) causes red-green color blindness.A. What is the genotype of a man with normal color vision whose father was color- blind? B. What is the genotype of a woman with normal color vision whose father was color-blind? C. If a woman who is colorblind marries a man with normal vision, what would you expect for the genotypes and phenotypes of their children? D. If a man is color-blind, which parent did he inherit the gene from? Explain your answer. E. Which parent does a man get all his x-linked genes from? F. If a woman is color-blind, what do you know about the genotypes and phenotypes of her parents? G. Are men more likely than women to get a genetic disease which is x-linked and dominant? Are they more likely to get a disease that is x-linked and recessive? Explain your answers. H. Can a man with normal color vision have a colorblind daughter? Explain your answer.…1. A human female "carrier" who is heterozygous for the recessive, sex-linked trait causing red-green color blindness (or alternatively, hemophilia), marries a normal male. What proportion of their male progeny will have red-green color blindness (or alternatively, will be hemophiliac)? * a. 100% b. 75% c. 50% d. 25% e. 0% 2. A human female "carrier" who is heterozygous for the recessive, sex-linked trait red color blindness, marries a normal male.What proportion of their female progeny will show the trait? * a. All b. ½ c. ¼ d. 0 e. 3/4 3. Women have sex chromosomes of XX, and men have sex chromosomes of XY. Which of a man's grandparents could not be the source of any of the genes on his Y-chromosome? * a. Father's Mother b. Mother's Father c. Father's Father d. Mother's Mother, Mother's Father, and Father's Mother e. Mother's Mother 4. Male-pattern baldness is an example of a sex-influenced trait. The baldness allele, which causes hair loss, is influenced by the hormones…