4. Grignard reagents are powerful nucleophiles that will react with a variety of electrophiles such as alkyl halides but ALSO act as strong bases, especially when they are sterically hindered. What would be the MAJOR organic product of the reaction below? Show a curved arrow mechanism for this transformation and give a mechanism type/name (E1, E2, SN1, SN2, 1,2-addition or nucleophilic acyl substitution). +MgBr tor -Br 1. 2. H₂O*

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter19: Eas: Electrophilic Aromatic Substitution
Section: Chapter Questions
Problem 24E
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4. Grignard reagents are powerful nucleophiles that will react with a variety of electrophiles such as
alkyl halides but ALSO act as strong bases, especially when they are sterically hindered. What would
be the MAJOR organic product of the reaction below? Show a curved arrow mechanism for this
transformation and give a mechanism type/name (E1, E2, SN1, SN2, 1,2-addition or nucleophilic
acyl substitution).
for
-Br
+MgBr
1.
2. H₂O*
Transcribed Image Text:4. Grignard reagents are powerful nucleophiles that will react with a variety of electrophiles such as alkyl halides but ALSO act as strong bases, especially when they are sterically hindered. What would be the MAJOR organic product of the reaction below? Show a curved arrow mechanism for this transformation and give a mechanism type/name (E1, E2, SN1, SN2, 1,2-addition or nucleophilic acyl substitution). for -Br +MgBr 1. 2. H₂O*
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