4. Ionization of Amino Acids. Each ionizable group of an amino acid can exist in one of two states, charged or neutral. The electric charge on the functional group is determined by the relationship between its pk, and the pH of the solution. This relationship is described by the Henderson-Hasselbalch equation. The amino acid histidine has a side chain for which the pk, is 6.0. Calculate what % of the histidine side chains will carry a positive charge at pH 5.3.

Principles of Modern Chemistry
8th Edition
ISBN:9781305079113
Author:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Publisher:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler
Chapter16: Solubility And Precipitation Equilibria
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4. Ionization of Amino Acids. Each ionizable group of an amino acid can exist in one of two states, charged or neutral.
The electric charge on the functional group is determined by the relationship between its pk, and the pH of the solution.
This relationship is described by the Henderson-Hasselbalch equation. The amino acid histidine has a side chain for which
the pk, is 6.0. Calculate what % of the histidirie side chains will carry a positive charge at pH 5.3.
Transcribed Image Text:4. Ionization of Amino Acids. Each ionizable group of an amino acid can exist in one of two states, charged or neutral. The electric charge on the functional group is determined by the relationship between its pk, and the pH of the solution. This relationship is described by the Henderson-Hasselbalch equation. The amino acid histidine has a side chain for which the pk, is 6.0. Calculate what % of the histidirie side chains will carry a positive charge at pH 5.3.
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