5-Bromouracil is a compound that is known to induce point mutations in DNA. 1) Out of A/C/G/T as drawn, which nucleobase pairs best with 5-bromouracil? Briefly explain why?    ii) The bromine of 5-bromouracil stabilises the alternative tautomeric form of the lactam at position 4. Describe in words the structure of this alternative lactim tautomer of 5-bromouracil.    iii) Identify the nucleobase (A/C/G/T) which can best base pair with this alternative tautomer.

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A:

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A:

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.