5. Calcium (Ca²+) binding to the protein calmodulin (CaM) is given by the mechanism: k=9.5x107 M-1 S-1 Ca²+ + CaM Ca/CaM at 298 K

Chemistry: The Molecular Science
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Author:John W. Moore, Conrad L. Stanitski
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Chapter11: Chemical Kinetics: Rates Of Reactions
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5. Calcium (Ca²+) binding to the protein calmodulin (CaM) is given by the mechanism:
k=9.5x107 M-1 S-1
Ca²+ + CaM
Ca/CaM
at 298 K
a. Calculate the initial rate of formation of Ca/CaM if [Ca/CaM]o = 0 and [Ca²+] = [CaM] =
1.0 x 10-5 M at 298 K. Do the same if [Ca²+] = [CaM]o = 1.0 × 10-7 M.
b. Write a general expression to calculate the concentration of Ca/CaM as a function of time
([Ca/CaM](t)) by assuming that [Ca²+] = [CaM]o and [Ca/CaM]o = 0.
Transcribed Image Text:5. Calcium (Ca²+) binding to the protein calmodulin (CaM) is given by the mechanism: k=9.5x107 M-1 S-1 Ca²+ + CaM Ca/CaM at 298 K a. Calculate the initial rate of formation of Ca/CaM if [Ca/CaM]o = 0 and [Ca²+] = [CaM] = 1.0 x 10-5 M at 298 K. Do the same if [Ca²+] = [CaM]o = 1.0 × 10-7 M. b. Write a general expression to calculate the concentration of Ca/CaM as a function of time ([Ca/CaM](t)) by assuming that [Ca²+] = [CaM]o and [Ca/CaM]o = 0.
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