5. Consider the use of GWAS to identify mutations that contribute to an increased risk of pancreatic cancer or to pancreatic cancer phenotypes. For a GWAS you have access to two populations: those with cancer, those without. What results would you expect to find if the DNA samples were taken from non-cancer tissues from both populations? How would this compare to results if you used DNA from cancer samples (pancreatic cancer biopsy) vs. healthy pancreatic tissue? State any assumptions you are making.

5. Consider the use of GWAS to identify mutations that contribute to an increased risk of pancreatic cancer or to pancreatic cancer phenotypes. For a GWAS you have access to two populations: those with cancer, those without. What results would you expect to find if the DNA samples were taken from non-cancer tissues from both populations? How would this compare to results if you used DNA from cancer samples (pancreatic cancer biopsy) vs. healthy pancreatic tissue? State any assumptions you are making.

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter19: Genomes And Proteomes

Section: Chapter Questions

Problem 8TYK

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