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- Which of the following effectively describes the situation of someone with an inherited predisposition to cancer such as familial adenomatous polyposis or BRCA-associated familial breast cancer? Choose all that apply a) If they get malignant cancer, somatic mutations will not have been a factor b) Their cancer will most likely arise in their germ cells, not their somatic cells c) None of the answers effectively describes the situation d) Every cell of their body contains a gain-of-function allele of an oncogene e) Most cells in their body contain multiple cancer-causing mutations f) Every cell of their body contains a defective, loss-of-function allele of a tumor suppressor geneWhich of the following types of mutations are advantageous to cancer cell growth? a. Those resulting in defective mismatch repair b. Inherited defects in double-strand DNA repair c. A defect in nucleotide-excision repair d. A, B, and C e. None of the aboveone question with multiple parts! 1A) If you were a cancer biologist interested in developing new drugs that will slow down cancer cell metastasis, which of the following strategies would be most effective? a)Develop an activator of mitosis b)Make Her2 protein that is more active on the surface of the cancer cells c) Develop a molecule that increases telomerase activity d) Gene therapy to add a mutated p53 gene to the cancer cells 1B) You are a genetic counsellor, and a couple comes to you with concerns that if they have a child together the child could have the X-linked recessive disease Duchene muscular dystrophy. The man has the disease whereas the woman is a carrier. Which of the following would be a true statement to tell them? a) 100% of their male offspring will likely be carriers of the recessive allele that causes the disease b) 75% of their female offspring will likely be carriers of the recessive allele that causes the disease c) 100% of their male offspring will likely…
- Which of the following must scientists understand in order to create effective cancer treatments? Select all that apply. a why cancer is difficult to treat b where cancer originated c how cancer cells multiply d how cancer cells growDraw a schematic diagram of how we can Treatment Cancer by using gene therapy? Please answer at your own words,please..Draw a diagram of how we can treatment the Cancer by using gene therapy? Please draw at your own hands.
- Which of the following statements is true about the effects of mutations in somatic cells and gametes? A. Only mutations in gametes can affect future generations. B. Only mutations in somatic cells can affect future generations. C. Neither mutations in somatic cells or gametes can affect future generations. D. Mutations in both somatic cells and gametes can affect future generations.Many of the mutations in cancer samples are not necessarily driver mutations, but rather passenger mutations that are along for the ride. Just because the tumors with a strong environmental component possess a higher frequency of mutations does not mean more oncogenes or more failure of tumor suppressors is occurring. Hematologic childhood cancers have a lower frequency of mutations than tumors with a strong environmental component such as lung cancers and melanoma; WHY?Sequencing the human genome, the development of microarray technology, and personal genomics promise to improve our understanding of normal and abnormal cell behavior. How are these approaches dramatically changing our understanding and treatment of complex diseases such as cancer?
- Why would a scientist wish to induce mutations? a. to increase the number of mutated phenotypes b. to create mutations in specific genes c. to test for carcinogen activity d. to create tumors for cancer research e. because she was crazier than a mutated bedbugList the agents in the environment that can change DNA or increase the frequency of mutations. 2. Define mutation. 3. Define a Point mutation and give an example. 4. What is sickle cell anemia and what causes it. 5. What is nondisjunction? How does nondisjunction cause disorders? 6. What is Gene translocation? 7. Would a mutation in one of your muscle cells affect your offspring? Why or why not? 8. What 3 things can individuals do to protect themselves from developing mutations?Although it is well known that X-rays cause mutations, they are routinely used to diagnose medical problems, including potential tumors, broken bones, and dental cavities. Why is this done? What precautions need to be taken?