Could you please help with these questions? Thank you! 59. Which is the expected product in the following reaction sequence?1. HC=C: Nat2. H2O, Hбон3. H2 (excess), Pd-C(A)HY "HH3CHH3C(C)(D)60. Which curved arrows correctly show the trajectory of attack of the hydroxide ion on the epoxide leading to its ring opening?(A)(C)HOHOHHY 'HH3C НH'YH3C(В)(D)"HH-OHOHOH(B)

-> nucleophile can open epoxide ring from less hindered side. -> H2/pd is reducing agent which…

59. Which is the expected product in the following reaction sequence? 1. HC=C: Nat 2. H2O, H 3. H₂ (excess), Pd-C HY н Н3С H H3C (B) 60. Which curved arrows correctly show the trajectory of attack of the hydroxide ion on the epoxide leading to its ring opening? (A) H OH OH HY 'H H3C H Η H3C бон (A) (В) ан Н- (0) ОН OH OH مجھے سکتے

59. Which is the expected product in the following reaction sequence? 1. HC=C: Nat 2. H2O, H 3. H₂ (excess), Pd-C HY н Н3С H H3C (B) 60. Which curved arrows correctly show the trajectory of attack of the hydroxide ion on the epoxide leading to its ring opening? (A) H OH OH HY 'H H3C H Η H3C бон (A) (В) ан Н- (0) ОН OH OH مجھے سکتے

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter22: Reactions Of Benzene And Its Derivatives

Section: Chapter Questions

Problem 22.14P

See similar textbooks

Similar questions

9. Product of the reaction of nitrobenzene with sulfuric acid in the presence of oleum at 60 °C:a) o-nitro benzenesulfonic acidb) m-nitro benzenesulfonic acidc) p-nitro benzenesulfonic acidd) None of the above 10. Due to their ability to move through ducts or pipes, they are generally called fluids:a) Solidsb) Solid mixturesc) Gasesd) Liquids and gases
8.29 Give the mechanistic symbols (Sn1, Sn2, E1, E2) that are most consistent with each of the following statements: (j) Alkyl iodides react faster than alkyl bromides in reactions that proceed by these mechanism
Rank the species below in order of increasing nucleophilicity in protic solvent. I. H2O II. CH3S— III. CH3COO— IV. t-BuO— I, II, IV, III I, III, II, IV I, III, IV, II I, II, III, IV
Which of the following statements about terminal alkynes is FALSE?I I. A geminal dihalide is produced by the hydrohalogenation reaction.II. The proton in the terminal carbon is acidic but just slightly.III.They create an aldehyde when they react with H2O, H2SO4, and HgSO4.IV. A silver acetylide is formed after treatment with alcoholic AgNO3.
8.29 Give the mechanistic symbols ( Sn1, Sn2, E1, E2) that are most consistent with each of the following statements: (d) The substitution product obtained by sovolysis of tert-butyl bromide in ethanol arises by this mechanism (e) In ethanol that contains sodium ethoxide, tert-butyl bromide reacts mainly by this mechanism (f) These reaction mechanisms represent concerted processes
The reaction of 2-ethyl-1-pentene with Br2, with H2 + Pd/C, or with R2BH/THF followed by aqueous HO- + H2O2 leads to a racemic mixture. Explain why a racemic mixture is obtained in each case.
4.34 Assuming that the rate-determining step in the reaction of cyclohexanol with hydrogenbromide to give cyclohexyl bromide is unimolecular, write an equation for this step. Use curvedarrows to show the flow of electrons.
Triethyloxonium tetrafluoroborate, (CH3CH2)3O+ BF4 −, is a solid with melting point 91–92 °C. Show how this reagent can transfer an ethyl group to a nucleophile (Nuc:−) in an SN2 reaction. What is the leaving group? Why might this reagent be preferred to using an ethyl halide?
D. N. Kursanov, a Russian chemist, proved that the bond that is broken in the hydroxide-ion-promoted hydrolysis of an ester is the acyl C¬O bond, rather than the alkyl C¬O bond, by studying the hydrolysis of the following ester under basic conditions: a. What products contained the 18O label?b. What product would have contained the 18O label if the alkyl C¬O bond had broken?
Provide a step-wise synthesis for the following: image 1 The last step of the synthesis needs to be a nucleophilic aromatic substitution reaction with a secondary amine.
The base-promoted rearrangement of an a-haloketone to a carboxylic acid, known as the Favorskii rearrangement, is illustrated by the conversion of 2-chlorocyclohexanone to cyclopentanecarboxylic acid. Jo Han Sow La NaOH, THF O Nat H3O+ OH NaOH, THF The mechanism involves the following 5 steps: -ō cyclopropanone intermediate 1. Abstraction of a proton to form enolate anion 1; 2. Formation of a cyclopropanone intermediate 2 with expulsion of chloride ion; 3. Addition of hydroxide ion to form tetrahedral intermediate 3; 4. Collapse of the tetrahedral intermediate and breakage of the three-membered ring to form carbanion intermediate 4; 5. Proton transfer to form the rearranged carboxylic acid. For the following reaction, draw the reaction out on paper, and then draw the structure of cyclopropanone intermediate 2 in the window. 1. NaOH, THF 2. H3O* OH
In Problem 7.28, we saw this two-step sequence in Johnsons synthesis of the steroid hormone progesterone. Propose a structural formula for the intermediate formed in Step 3 and a mechanism for its conversion in Step 4 to progesterone.