8. Consider the structure of Quinine, an antimalarial drug below with an optical rotation of -165°. (a) Draw the structure and identify (by a star) all stereogenic centres present in the Quinine structure. (b) Calculate the ee of the solution with the following [a] values: -50 and -120 (c) For each calculated ee, compute percentage of each enantiomer present. (d) What is the enantiomer of Quinine? (e) If the solution contains 80% quinine and 20% of it enantiomer, what is the ee of the solution?
8. Consider the structure of Quinine, an antimalarial drug below with an optical rotation of -165°. (a) Draw the structure and identify (by a star) all stereogenic centres present in the Quinine structure. (b) Calculate the ee of the solution with the following [a] values: -50 and -120 (c) For each calculated ee, compute percentage of each enantiomer present. (d) What is the enantiomer of Quinine? (e) If the solution contains 80% quinine and 20% of it enantiomer, what is the ee of the solution?
Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter22: Reactions Of Benzene And Its Derivatives
Section: Chapter Questions
Problem 22.59P
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