A 79 kg man is admitted to hospital following a suspected overdose of drug G. When he is admitted to hospital on the 3rd October at 23:00 his plasma concentration of drug G is 12 mg/mL. Given that the half-life (t½) of drug G is 10.5 hours. What would you expect his plasma concentration of drug G to be at 17:00 on the 5th October? Give the answer in microg/ml. (You may assume that the distribution is complete and the elimination is described by a 1storder

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 7.7P
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 A 79 kg man is admitted to hospital following a suspected overdose of drug G. When he is admitted to hospital on the 3rd October at 23:00 his plasma concentration of drug G is 12 mg/mL. Given that the half-life (t½) of drug G is 10.5 hours. What would you expect his plasma concentration of drug G to be at 17:00 on the 5th October? Give the answer in microg/ml. (You may assume that the distribution is complete and the elimination is described by a 1storder process.)

 

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