A 71-year-old man with enterococci infection is started treatment with 240 mg of intravenous gentamicin. It has a volume of distribution of 30 L, a half-life of 4 hours, and demonstrates first-order and one-compartment kinetics. Which of the following is the most likely serum drug concentration 8 hours later?     0.5 mg/L      1 mg/L      1.5 mg/L      2 mg/L      3 mg/L

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 7.9P
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A 71-year-old man with enterococci infection is started treatment with 240 mg of intravenous gentamicin. It has a volume of distribution of 30 L, a half-life of 4 hours, and demonstrates first-order and one-compartment kinetics. Which of the following is the most likely serum drug concentration 8 hours later?

   

0.5 mg/L 

   

1 mg/L 

   

1.5 mg/L 

   

2 mg/L 

   

3 mg/L

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