a) A protein gains a mutation of a surface exposed residue. The mutation is Arg --> Leu. Based on the sequence of the protein when it folds the Leu remains on the surface of the protein. What is the change in chemical characteristic of the amino acid caused by this mutation? b) Briefly explain any entropic consequences of this mutation. (2 sentences MAX) c) What might happen in order to overcome these entropic consequences and how would that affect the cell? (1-2 sentences)

a) A protein gains a mutation of a surface exposed residue. The mutation is Arg --> Leu. Based on the sequence of the protein when it folds the Leu remains on the surface of the protein. What is the change in chemical characteristic of the amino acid caused by this mutation? b) Briefly explain any entropic consequences of this mutation. (2 sentences MAX) c) What might happen in order to overcome these entropic consequences and how would that affect the cell? (1-2 sentences)

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter10: From Proteins To Phenotypes

Section: Chapter Questions

Problem 20QP: If an extra nucleotide is inserted in the first exon of the beta globin gene, what effect will it...

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