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- Radiolabeling with 14C-Glutamate Describe the labeling pattern that would result from the introduction into the TCA cycle of glutamate labeled at Cy with 14C.Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited by· NIADH. Pyruvate dehydrogenase is inhibited by AΤΡ. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.In the context of fatty acid oxidation to acetyl CoA, indicate whether each of the following substances is involved in (1) fatty acid activation, (2) fatty acid trans-port, or (3) b-oxidation pathway. More than one choice may be correct in a given situation. a. AMp b. FAD c. Acyl CoA d. H2O
- Consider the docosanoic acid, C21H43CO2H a. Label the a and B carbons b. Draw the acyl CoA derived from this fatty acid c. How many acetyl CoA molecules are formed by complete B-oxidation? d. How many cycles of B-oxidation are needed for complete oxidation? e. How many molecules of ATP are formed from the complete catabolism of this fatty acid?22. Which hormone is NOT derived from cholesterol? a. oxytocin b. testosterone c. both a and b d. neither a nor b 23. Which lipoprotein mostly contains triacyglycerol (TAGs)? a. HDL b. VLDL c. LDL d. chylomicrons 24. Which enzyme in cholesterol synthesis is inhibited by statins? a. HMG-CoA synthase b. HMG-CoA reductase c. both a and b d. neither a nor b 25. Which lipoprotein prevents the formation of plaque in the artery? a. HDL b. VLDL c. LDL d. chylomicrons 26. In which test/s will triacylglycerol yield a positive result? a. acrolein b. translucent spot c. both a and b d. neither a nor b 27. In which solvent will corn oil be soluble? a. hexane b. benzene c. both a and b d. neither a nor b 28. In which test/s will cholesterol yield a positive result? a. acrolein b. Huble's test c. both a and b d. neither a nor b 29. Which sample would test negative in saponification test? a. cholesterol b. 18:2 fatty acid c. both a and b d. neither a nor b 30. What test could distinguish…1.a. Given what you know about glycolysis and gluconeogenesis, does it make sense that insulin activates PDH phosphatase? Why? b.How do vitamins increase to the breadth of chemical reactions available within a biological system?
- If the w-carbon atom of a fatty acyl CoA molecule with a C18 chain is labeled with C14, how many rounds of β-oxidation are required to produce a radioactively labeled acetyl CoA? a. four b. five c. six d. seven e. eight f. nineOrder the steps that results in a triacylglycerol containing two palmitic acids and one stearic acid. a. Diacylglycerol reacts with an fatty-acyl-CoA b. Phosphate is remove from phosphatidic acid to form diacylglycerol c. Two of the fatty acyl-CoAs react with glycerol-3-phosphate d. An elongase produce stearic acid e. Stearoyl-CoA is synthesized…1. Select the INCORRECT statement about Glutamate dehydrogenase : a. Catalyzes the removal of NH4+ into glutamate b.Catalyzes the incorporation of NH*4 into a-ketoglutarate c. Catalyzes the removal of NH*4 from glutamate C d. Catalyzes the incorporation of NH'4 into a-keto acid
- Starting with acetyl-S-enzyme-1 and malonyl-CoA, how many molecules of acetyl- CoA are needed to synthesize an 18-carbon fatty acid (C18:0)? How many molecules of CO2 are released in this process?The reaction of acetyl-CoA and oxaloacetate in the TCA cycle forms a. 5-carbon α-ketoglutarate b. 4-carbon Succinyl-CoA c. 6-carbon citrate d. 6-carbon α-ketoglutarate e. 4-carbon citrateWhich one of the following will function to inhibit CPT1? A.palmitoyl-CoA B.citrate C propionyl-CoA D.acetyl-CoA E malonyl-CoA