A bacterial protein-coding gene has a standard consensus promoter and a rho-independent terminator. A mutation deletes the base pairs at the +1 and +2 positions, including the transcription start site at +1. What will be the most likely effects, if any, on the transcript and the encoded polypeptide? Both the transcript and the polypeptide will be unchanged. The transcript will be 2 bases shorter; the polypeptide will be completely different due to a frameshift. The transcript will be 2 bases shorter; the polypeptide will be one amino acid shorter but otherwise unchanged. Transcription will not be initiated, so neither a transcript nor a polypeptide will be produced. The transcript will be 2 bases shorter; the polypeptide will be unchanged.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
A bacterial protein-coding gene has a standard consensus promoter and a rho-independent terminator. A mutation deletes the base pairs at the +1 and +2 positions, including the transcription start site at +1. What will be the most likely effects, if any, on the transcript and the encoded polypeptide?
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Both the transcript and the polypeptide will be unchanged. |
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The transcript will be 2 bases shorter; the polypeptide will be completely different due to a frameshift. |
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The transcript will be 2 bases shorter; the polypeptide will be one amino acid shorter but otherwise unchanged. |
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Transcription will not be initiated, so neither a transcript nor a polypeptide will be produced. |
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The transcript will be 2 bases shorter; the polypeptide will be unchanged. |
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