Tay Sachs disease is an autosomal recessive disease in which a protein – Hex A - is abnormal. To make the Hex A protein: The promoter and transcription termination sites are 33,000 base pairs apart. The Hex A protein has 600 amino acids 5’ and 3’ UTR’s are each 500 bp long. a)How many base pairs would you expect in the final mRNA? Show your work b)How many bases were spliced out? Show your work
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
- Tay Sachs disease is an autosomal recessive disease in which a protein – Hex A - is abnormal. To make the Hex A protein:
- The promoter and transcription termination sites are 33,000 base pairs apart.
- The Hex A protein has 600 amino acids
- 5’ and 3’ UTR’s are each 500 bp long.
a)How many base pairs would you expect in the final mRNA? Show your work
b)How many bases were spliced out? Show your work
Molecular Biology is the branch of biology that deals with a study of the composition, arrangement, and synergies of cellular molecules, such as nucleic acids (DNA and RNA) and proteins that conduct the biological processes necessary for the cell's functions and sustenance.
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