Answered: A mutant allele in persons with…

Name: A mutant allele in persons with familial hypercholesterolemia (FH) cau
Uploaded: 2024-03-20T06:42:55.000Z
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Description: A mutant allele in persons with familial hypercholesterolemia (FH) causes death due to a lack of liver receptors for LDL. Susceptible persons have half the normal number of receptors, while other individuals have the normal number of receptors. In a

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter20: Chromosomes And Human Genetics

Section: Chapter Questions

Problem 7CT: The following pedigree shows the pattern of inheritance of red-green color blindness in a family....

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A mutant allele in persons with familial hypercholesterolemia (FH) causes death due to a lack of liver receptors for LDL. Susceptible persons have half the normal number of receptors, while other individuals have the normal number of receptors. In a phenotypically normal couple, the man had a female 1 cousin (on his father’s side) who died from FH; the woman had a maternal uncle with FH.

a. What is the probability that neither of the couple might be susceptible.

b. What is the probability that one of them might be susceptible, but the other is not.

c. What is the probability that they will have an FH child if a test discloses that both of them are susceptible.

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