A physician administers 250 mg of drug X to a patient as an oral pill and finds that only 50 mg of the drug becomes bioavailable. If it is known that absorption of the drug in the GI tract is 80%, what percent of the drug absorbed is lost to the first pass of the liver? A) 80% B) 60% C) 25% D) 20% E) 75%

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter30: Nutrition
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A physician administers 250 mg of drug X to a patient as an oral pill and finds that only 50 mg of the drug becomes bioavailable. If it is known that absorption of the drug in the GI tract is 80%, what percent of the drug absorbed is lost to the first pass of the liver? A) 80% B) 60% C) 25% D) 20% E) 75%
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