FBBS 2 Worksheet 2NameHINT: when you are explaining mechanisms affected by mutations, think about molecular interactions, orenzymatic functions, or conformational changes that are involved in the normal pathways, since these are theaspects most likely to be affected by mutations or drugs, or viral proteins.If a consequence of a mutation/drug/virus results in a cdk being more frequently active, then the cell cycle willproceed at the given checkpoint. If the consequence of a mutation/drug/virus results in a cdk beinginactivated or inhibited, then the cell cycle is stopped at the given checkpoint.cdc2kinaseInactive1) Given the following diagram of a mechanism regulating the cell cycle of the fission yeast S. pombe.Interphase (G₂)CAKWee1CyclinThr161-P Tyr15-Pcdc2kinaseCyclinInactiveThr161-Pcdc25G₂ fissionyeast cellcdc2kinaseCyclinActiveInterphase (G₁)Post-mitoticfissionyeast cellsDatecdc2kinaseDr. MilaniInactiveCyclinDegradationA) Predict the consequences on the cell cycle if the amino acid tyrosine15 of cdc2 was mutated to an alanine,which cannot be phosphorylated. And explain clearly the reason for this prediction. (just talk about the cellcycle, keep your description of a phenotype for part (B)B) Describe and explain the possible phenotype of the yeast strain carrying Tyrosine15 to alanine mutation incdc2, compared to wild type yeast. (use what you learn about S. pombe mutants in class)

Name: FBBS 2 Worksheet 2NameHINT: when you are explaining mechanisms affect
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Description: FBBS 2 Worksheet 2NameHINT: when you are explaining mechanisms affected by mutations, think about molecular interactions, orenzymatic functions, or conformational changes that are involved in the normal pathways, since these are theaspects most like

Cell cycle regulation is an important step in all organisms that ensures proper cell growth and…

Science

Biology

A) Predict the consequences on the cell cycle if the amino acid tyrosine 15 of cdc2 was mutated to an alanine, which cannot be phosphorylated. And explain clearly the reason for this prediction. (just talk about the cell cycle, keep your description of a phenotype for part (B) B) Describe and explain the possible phenotype of the yeast strain carrying Tyrosine 15 to alanine mutation in cdc2, compared to wild type yeast. (use what you learn about S. pombe mutants in class)

A) Predict the consequences on the cell cycle if the amino acid tyrosine 15 of cdc2 was mutated to an alanine, which cannot be phosphorylated. And explain clearly the reason for this prediction. (just talk about the cell cycle, keep your description of a phenotype for part (B) B) Describe and explain the possible phenotype of the yeast strain carrying Tyrosine 15 to alanine mutation in cdc2, compared to wild type yeast. (use what you learn about S. pombe mutants in class)

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter15: Dna Technology And Genomics

Section15.1: Dna Cloning

Problem 2C: Different forms of a protein are produced in the liver and in the brain by alternate splicing of its...

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