Describe a synthetic plan with justification of the sequence of reactions you would take to complete the synthesis of 1. Suggest reagents A retrosynthetic analysis of 1 was undertaken suggesting a forward synthesis starting fromcompounds 2, 5 and 6.F3CF3COHH2NN.BrA (a)(b)NH21HO6.2. In order to complete the synthesis of 1 from compounds 2, 3, and 4, describe ad)synthetic plan with suitable justification of the sequence of reactions you wouldundertake. Suggest suitable reagents for all your proposed reactions.CF3OHOHCF3H2NBrH.NH2(1)(3)(4)(2)

We have to synthesize organic compound 1 :

Answered: A retrosynthetic analysis of 1 was…

A retrosynthetic analysis of 1 was undertaken suggesting a forward synthesis starting from compounds 2, 5 and 6. F30 OH F3C. OH H. H2N. Br (а) (b) NH2 1 3 но

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter22: Reactions Of Benzene And Its Derivatives

Section: Chapter Questions

Problem 22.63P

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Concept explainers

Diol

In chemistry there are so many chemical compounds that have a hydroxyl group but a chemical compound having two hydroxyl groups (-OH) is termed as a diol. It also implies the presence of two alcohols whereas polyols contain two or more than two hydroxyl groups (-OH). Glycol or 1,2-diol is an aliphatic diol that has two alcohol groups on adjacent carbon atoms. In industries, the most commonly used diol is ethylene glycol.

Question

Describe a synthetic plan with justification of the sequence of reactions you would take to complete the synthesis of 1. Suggest reagents

A retrosynthetic analysis of 1 was undertaken suggesting a forward synthesis starting from
compounds 2, 5 and 6.
F3C
F3C
OH
H2N
N.
Br
A (a)
(b)
NH2
1
HO
6.
2.

In order to complete the synthesis of 1 from compounds 2, 3, and 4, describe a
d)
synthetic plan with suitable justification of the sequence of reactions you would
undertake. Suggest suitable reagents for all your proposed reactions.
CF3
OH
OH
CF3
H2N
Br
H.
NH2
(1)
(3)
(4)
(2)

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