A variety of abnormalities in the numbers of sex chromosomes exist because of nondisjunction during gametogenesis. Discuss the signs and problems associated with conditions such as Klinefelter and Turner syndromes.

Q: Sex determination of child is done by whose chromosome?

A: Chromosomes are the thread like structures which are located in the nucleus. There are 23 pairs of…

Q: Which of the following statements best describes the inheritance pattern of an X-linked dominant…

A: Pedigree is a family chart showing the inheritance of a particular trait through several generations…

Q: Describe the individuals with the following chromosomal abnormalities: Trisomy at chromosome 21 XXY…

A: Chromosomes are the  condensed forms of chromatin seen during the cell division. They were…

Q: What environmental factors may increase incidence of chromosomal abnormalities? Name at least three.

A: Chromosomal abnormalities or aberration is defined as the defect in the structure or the number…

Q: What is the difference between sex-linked disease/disorder and sex chromosome disease/disorder?

A: Sex chromosomes are in the form of XX in females and in males, it is in the form of XY. When there…

Q: Under what conditions does a female acquire anX-linked recessive disorder?

A: The dominant allele can be defined as the type of allele which is expressed in the phenotype even if…

Q: A boy with Klinefelter syndrome (47,XXY) is born to a mother who is phenotypically normal and a…

A: Meiosis is a type of cell division that occurs during gamete formation. It involves the reduction of…

Q: A man with thalassemia minor marries a normal woman.  What phenotypic ratios of thalassemia-affected…

A: Thalassemia is an inherited blood disorder in which the body makes an abnormal form of hemoglobin.…

Q: Give several examples of chromosome number disorders.

A: Genetic disorders are defects that are caused by any genetic mechanism like mendelian genes ,multi…

Q: Which characteristics are associated with Duchenne muscular dystrophy? O Y-linked genetic…

A: Genetics is the study of genes and their normal morphology and functioning , gene is the basic unit…

Q: Please explain Androgen Insensitivity Syndrome (ALS). What is the phenotype of these individuals?…

A: The common etiology of aberrant sexual development, androgen insensitivity syndrome, results in a…

Q: Which of the following can arise from a zygotic mitotic problem in an individual with a normal XY…

A: Following condition arised due to Error in zygote mitosis in an individual with XY genotype.

Q: Describe four X-linked recessive disorders

A: Recessive Disorder : To have an autosomal recessive we inherit two mutated genes ,one from each…

Q: What is Down's syndrome? Give its symptoms and cause. Why is it that the chances of having a child…

A: Human genetic disorders are caused by the absence, excess, or abnormal arrangement of one or more…

Q: Can a woman who is affected by an X-linked dominant disorder have a child who is not affected? Why…

A: In physiology, X-linked dominant disorder is defined as genetic disorder occurs due to X chromosome…

Q: What is meant by Trisomy 21 ?

A: Chromosomal abnormalities are the type of genetic disorders caused due to the change in one or many…

Q: . Researchers discovered recently that the sole functionof the SRY protein is to activate an…

A: There are various genetic disorders that develop due to anomalies in sex chromosomes. They normally…

Q: Why is the chances of having a child with down's syndrome increases if the age of mother exceed…

A: Down’s syndrome is basically an autosomal genetic disorder that is caused by trisomy at chromosome…

Q: Why do most cases of Down syndrome originate from the mother? And how is this linked to maternal age…

A: Down syndrome also called "trisomy 21" is a condition in which a child is born having an additional…

Q: On the basis of the information provided, is the inheritance of haemophilia:   autosomal or…

A: Hemophilia is a form of clotting deficiency due to lack of clotting factor 8 and 9. Most affected…

Q: Why is autosomal Monosomy lethal?

A: Most living species have DNA as their genetic material. It is the cell's information centre,…

Q: Autosomal aneuploidy is usually lethal due to genetic_________

A: Introduction  Chromosomal aberrations are the common cause of abnormal development of the embryo or…

Q: How to reduce chromosomal abnormalities?

A: Chromosomal abnormalities can be structural or numerical. A structural chromosomal abnormality means…

Q: If a father is unaffected by an X-linked condition and the mother is a carrier, what is the…

A: Genetics is the branch of biology that deals with the study of heredity and variations. Gregor…

Q: Identify a disorder caused by a chromosomal abnormality and how the disorder affects the individuals…

A: Chromosomal abnormality are one of the main reasons for many inherited disorders and traits, and…

Q: What is incomplete penetrance and what causes it?

A: Introduction  Any gene have two alleles pairs viz. Dominant or Recessive. The allele which gets…

Q: What is the most common chromosomal disorder?

A:

Q: What is Trisomy test?

A: The chromosomes are the thread like structure that contains hereditary information in the form of…

Q: A woman is affected with Prader-Willi syndrome due to a deletion that includes both the Angelman…

A: Both the Prader-willi syndrome and Angelman syndrome is caused by deletion of of longer arm (q arm)…

Q: Can a son be a carrier for an X-linked trait? Explain.

A: The genetic makeup of an offspring is determined by the genetic makeup of both parents; that is, the…

Q: Phenotypes that are related to the sex can be classified as: sex-linked, sex -limited, or…

A: An example for the sex linked trait is the haemophilia. The traits that are carried on the X…

Q: A female with Turner syndrome is denoted by which of the following cytogenetic notations?

A: Turner syndrome is a chromosomal disorder that occurs only in females and causes a variety of…

Q: Why does a single X chromosome cause infertility and other abnormalities in Turner Syndrome…

A: Turner syndrome (TS) is a genetic disorder that mostly affects females. The clinical features of…

Q: What are chromosomal Defects. List and Explain any 5 of them.

A: Almost every cell in our body contains 23 pairs of chromosomes, for a total of 46 chromosomes. Half…

Q: Explain the meaning of trisomy 21.

A: Chromosomes: These are thread-like structures. These are located inside the nucleus of the cells.…

Q: Predict the phenotypes associated with the following mutant states. For each of the four conditions…

A: Gonadal determination of sexually indifferent gonads and genitalia involves a series of events…

Q: What are the  symptoms of chromosomal abnormalities?

A: The chromosomal abnormalities can be categorized into two types that are structural and numerical.…

Q: What is 47,XXX Syndrome ?

A: A syndrome is characterized by a collection of medical indications and symptoms that are related to…

Q: What are the possible effects of chromosomal mutations?

A: Malfunctioning of the kinetochore can lead to a chromosomal abnormality that is known as…

Q: Incontinentia pigmenti, a rare, X-linked dominant disorder inhumans, is characterized by swirls of…

A: Incontinentia pigmenti is a genetic disorder that damages the skin and is more frequent in females…

Q: Present clinical consequences of most commonly identified numerical chromosome abnormalities.

A: Chromosomes are thread like structures which are found in the nucleus of the eukaryotic cells. In…

Q: Give the typical sex-chromosome complement found in the cells of people with Turner syndrome, with…

A: Chromosome complement refers to the entire set of chromosomes in the nucleus of a cell in a…

Q: Indicate and explain at least three examples of abnormalities in genes and chromosomes

A: Three of the various abnormalities associated with genes and chromosomes encompass Schizophrenia,…

Q: What criteria or features are used to identify each chromosome by number?

A: *NOTE: Kindly repost for other question. Dear Student as per the guidelines we are supposed to…

Q: Differentiate a multifactorial disorder from a chromosomal disorder.

A: Multifactorial diseases are not confined and do not follow any specific pattern of single gene…

Q: Describe two mechanisms for causing uniparental disomy.

A: Describe two mechanism for causing uniparental disomy.

Q: identify two main themes underlying the phenomena of chromosomal changes?

A: Chromosome is a compact structure of a DNA molecule wrapped around some proteins. It is generally…

Q: With relevance to sex determination in humans, discuss: i) X chromosome inactivation; and ii)…

A: In humans, sex is determined by sex chromosomes( XX females xy males). the X and y chromosome harbor…

Q: Describe two mechanisms for causing uniparental disomy.

A: Uniparental disomy occurs when two copies of a chromosome are inherited from same parent, rather…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.