9. Obesity becomes epidemic in many countrics due to excessive food consumptionand reduced physical activity. The problem is that obesity has significanthealth implications. Therefore, interest in weight reduction is widespread.Orlistat, a modern anti-obesity drug, is a nonhydrolyzable structural analogof a triacylglycerol and powerful inhibitor of the enzyme required for digestionof TAG. Orlistat not only decreases fat absorption, but also stimulates theproduction of the YY peptide, which gives a satiety sensation, and slows downa food motion along the gastrointestinal traet. Explain the mechanisms ofOrlistat's action on the weight loss. For that answer the questions and do thefollowing tasks:a) what enzyme is being inhibited by Orlistat?b) draw the reaction, which happens in the small intestinal, where this drugworks as an inhibitor;c) what type of inhibition has Orlistat as it is the structural analog of atriacylglyccrol?d) describe the mechanism of weight loss after orlistat treatment.

Orlistat is being used as a weight-loss agent. It may decrease the absorption of fat-soluble…

a) what enzyme is being inhibited by Orlistat? b) draw the reaction, which happens in the small intestinal, where this drug works as an inhibitor; c) what type of inhibition has Orlistat as it is the structural analog of a triacylglycerol? d) describe the mechanism of weight loss after orlistat treatment.

a) what enzyme is being inhibited by Orlistat? b) draw the reaction, which happens in the small intestinal, where this drug works as an inhibitor; c) what type of inhibition has Orlistat as it is the structural analog of a triacylglycerol? d) describe the mechanism of weight loss after orlistat treatment.

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter6: Energy, Enzymes, And Biological Reactions

Section: Chapter Questions

Problem 9TYK: Which of the following statements about inhibition is true? a. Allosteric inhibitors and allosteric...

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