Q: Give a schematic diagram of how we can Treatment Hemophilia by using gene therapy?
A: Hemophilia is a sex linked genetic disorder that is characterized by inability to make adequate…
Q: Contrast gene paralogs with gene orthologs.
A: The functional and structural unit of inheritance is a gene. These are composed of DNA. There are…
Q: Illustrate and give the normal sequence and the mutated sequence in Leigh's syndrome
A: A disease is a state of unhealthiness of the physical body, mind and social interaction. A disease…
Q: Name the two types of mutagens, give an example for each, and briefly describe how they cause…
A: Mutagen is a physical or chemical agent that permanently changes genetic material,usually DNA , in…
Q: Distinguish between homologs, paralogs, and orthologs.
A: Homologs can be used to predict the functions of unknown proteins that can be understood from the…
Q: a. Which gene is mutated in individuals with sickle-cell anemia? b. What are the major symptoms of…
A: Hi! Thanks for your question. As you have posted multiple questions and have not mentioned which one…
Q: What type of mutation occurred in the gene sequence that resulted in white-fur bears
A: Polar bears have white fur to help them blend in with their surroundings. In Arctic conditions,…
Q: Using illustrations describe the structure of a typical cloning vector and discuss the functions of…
A: "Biotechnology" is the use of our knowledge of biological processes to the development of beneficial…
Q: a. What is(are) the difference(s) between orthologs and paralogs?
A: Homology the term used for any organism having relationship by common descent ancestor. If two or…
Q: Explain why loss-of-function mutations are frequently recessive, whereas gain-of-function mutations…
A: Mutation is an altered DNA sequence, which leads to changed gene product. Mutations are random and…
Q: Briefly explain the frameshift mutation ?
A: Mutation can be defined as the change that occurs in the DNA sequence which is caused by mistake or…
Q: suggest reasons for why DNA mutations are not all phenotypic.
A: Mutation is a change in nucleotide sequence of DNA which can occur either due to mistakes during DNA…
Q: What is a gene? Provide at least two different definitions and explain.
A: Gene is a segment of DNA (deoxyribonucleic acid) of an individual that is responsible for the…
Q: a. What is a genetic mutation? How do genetic mutations differ from somatic mutations? b. What…
A: “Since you have posted a question with multiple sub-parts, we will solve first three subparts for…
Q: Explain Deletion-insertion polymorphisms (DIPs)?
A: DIPs or Deletion-Insertion polymorphisms is defined as a large number of consistent genetic variants…
Q: define Silent mutations
A: point mutations result in inheritable changes that occur on a single random nucleotide on the DNA.…
Q: Explain the central dogma of genetics at the molecular level.
A: In literal sense, dogma refers to a definite set of principles or processes. Central dogma refers to…
Q: a) Explain the difference between a genome and a transcriptome. Do all cells in an organism have the…
A: The branch of biology includes the study of genes, their variation, and inheritance in organisms.…
Q: State and describe the benefits of using whole-genome sequencing for diagnosis.
A: The whole genome shotgun method involves cloning, followed by accurate computer sequencing of the…
Q: Explain about the Identification and Cloning of the Huntington Gene ?
A: Genetics is a part of science worried about the investigation of genes, genetic variety, and…
Q: A geneticist is trying to determine how many genes are found in a 300,000-bp region of DNA. Analysis…
A: Deoxyribonucleic acid (DNA) is the genetic material. Nucleosome is the packaging unit in eukaryotes.…
Q: How were the specific sequences of triplet codes determined experimentally?
A: The DNA genetic code comprises a set of rules and instructions to obtain proteins and molecules…
Q: Explain how paralogs and orthologs are produced
A: Gene is known to be the basic unit of heredity of all life forms. Most animals contain…
Q: Discuss why a genetic disease might have a particular age of onset.Would an infectious disease have…
A: Different genetic diseases result in different abnormalities in the human genome. A genetic disorder…
Q: What is the likely consequence of a frameshift mutation?
A: A mutation occurs/happens when the sequence/structure of DNA is altered. Mutations can occur as a…
Q: Briefly explain a. Ortholog b. B ion c. SILAC
A: Introduction :- ortholog in term of genomic studies is defined as the genes present in different…
Q: gene mutation
A:
Q: three different types of loss of function mutations and in each case explain how the mutation exerts…
A: A mutation is any alteration of the base sequence of the DNA or RNA. Since mutation alters the base…
Q: Explain why orthologs have sequences that are similar but not identical.
A: A homologous trait can be described as a homolog also spelled homologue. In terms of genetics, the…
Q: Explain Exceptional genetic codes?
A: A genetic code translates the genetic information encoded within the deoxyribonucleic acid (DNA) or…
Q: What is an ortholog?
A: The gene is a basic physical and functional unit of heredity. Genes are made up of DNA.The gene is a…
Q: Explain Null (amorphic) and leaky mutations (hypomorphic), hypermorphic and neomorphic mutations
A: Mutations (changes in a gene sequence) can result in mutant alleles that no longer produce the same…
Q: describe Deletion-insertion polymorphisms (DIPs)
A: Polymorphism: Many forms of a allele is termed as polymorphism. The polymorphism leads to the…
Q: Please explain the different type of mutations and how do they  occur?
A: Mutation is change taking place in sequence of DNA which can occur either because of mistake during…
Q: A. What is random mutagenesis? B. How many people a year die due to insecticide misuse and exposure?
A: Selective breeding practises having existed for crops ever since man started cultivation. So there…
Q: Discuss three potential benefits and three possible harmful effects of genetic modifications on…
A: Genome editing technologies enable scientists to make changes to DNA, leading to changes in physical…
Q: What is the Central Dogma of Molecular Genetics? What impact did the discovery of RNA tumor viruses…
A: The Central Dogma was first proposed in 1958 by Francis Crick. He was also the discoverer of the…
Q: a- What is genome assembly?
A: Sequence assembly is the process of matching & combining segments from a larger DNA sequence in…
Q: Provide one example of a clinical implication of a “silent mutation” that proven to have an effect…
A: Answer: SILENT MUTATIONS are the mutations in the DNA that do not have an observable effect on the…
Q: Compare and contrast orthologs and paralogs.
A: Genes are the basic structural and functional unit of heredity. They carry coded genetic information…
Q: Define the features recognition sequences ?
A: Restriction enzymes are endonucleases and digest the DNA molecules into smaller fragments.
Q: • Inversions alter the order, but not the number, of geneson a __________
A: The number and the structure of the chromosomes are maintained as such during the meiosis, however,…
Q: What is the function of the “junk DNA” in human genome? proper explanation and diagram
A: DNA (Deoxyribonucleic Acid) is the genomic material found in the cells of living organisms that help…
Q: Explain the concept of inherited molecular disease ?
A: A condition that deteriorates the normal functioning of the cells, tissues, and organs is known as…
Q: Explain the Detection of the sickle-cell mutation by sequencing of PCR products?
A: The disorder in which a group of red blood cells becomes sickle-shaped, it is known as sickle cell…
Q: a. Explain what hybridization is and how it is used in the Southern blot.b. Explain how gene probes…
A: Nucleic acids are chains made of a series of nucleotides. Nucleotides have the property of forming…
Q: explain about the Exceptional genetic codes
A: A set of rules that the cell uses to translate the mRNA into proteins is known as a genetic code.…
Q: Explain the process of determining the Gene Sequence ?
A: DNA sequencing can be outlined as the phenomenon which is used for determining the sequence of the…
Step by step
Solved in 3 steps
- B. Using the DNA sequence above, write a new DNA sequence from 3’ to 5’ that incorporates a transition leading to a silent mutation in the second amino acid. Bold or underline the nucleotide that has been changedWhen doing a lab that involves Extraction of Genomic DNA from adult Drosophila melanogaster. - What are the controls you should use and why use these? What is special about the genomic DNA? What do you expect to find (using these genomic DNA samples)? please help!What is Sanger sequencing? Why do we use ddNTP? How to read a DNA sequence gel? c. What is a cDNA seq (RNA seq)? d. What is the main difference between a genomic and a transcriptome study?