aa e ui8ag o1 pai 10,000 progeny were analyzed for each cross. Of 10,000 progeny, there were: Three linked genes (V, are etic map. ses wer 2207 recombinants between v and p 1489 recombinants between p and b 718 recombinants between b and v Use this information to determine the order of these genes on the chromosome (i.e. construct a genetic map)
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- You have already localized the genes to the same chromosome by deletion mapping, and now decide that the best way to accomplish the mapping is to conduct two simultaneous three-point testcross experiments. The genes you are investigating are as follows: N = round leaves, n = notched leaves; H = smooth stems, h = hairy stems; R = purple flowers, r = red flowers; B = grey seeds, b = black seeds; and Y = green pods, y = yellow pods. Earlier experiments you have done already established that gene B is in the middle of this gene cluster, so you design both three-point test crosses to include that gene. Cross #1 is designed as RrHhBb x rrhhbb while cross #2 is NnBbYy x nnbbyy. The results of both crosses are given in the table below. Based on the information given, determine the arrangement of these five genes including the position of each allele in the heterozygous fly and the distances between each pair of genes. (Hint: treat each experiment separately, knowing that gene B is in the…You conduct a series of two-point mapping crosses involving five genes located on chromosome III and obtain the following percentage of recombinant offspring: h-cu eyg-h eyg-cu rai-eyg rai-h rai-cu th-cu th-h th-eyg th-rai 23.5% 9.0% 14.5% 18.5% 9.5% 33.0% 6.8% 16.7% 7.7% 26.2% The rai gene is at the near end of the chromosome. Gene th is between which two genes? A. eyg and cu B. rai and cu C. h and cu D. rai and hThe first task in mapping genes in three-point testcross is to determine their order on the chromosome and then to determine the locations of the cross overs. There are two ways, one can determine which gene is in the middle. Describe both the methods that explains how one would determine the middle locus- You can use three genes A, B, and C. You can decide whatever phenotype each gene encodes.
- In a cross between mice the genotypes AB/ab x ab/ab, what is the recombination frequency if the progeny numbers are 72 AB/ab, 68 ab/ab, 17 Ab/ab, and 21 aB/ab? The alleles are shown for each chromosome, separated by a slash (/)Two genes, A and B, are 10 map units apart along the same chromosome. A cross was made between AAbb and aaBB individuals to produce AaBb F1 offspring. The F1 offspring were then crossed to aabb individuals to yield an F2 generation. What would be the genotype(s) of F2 offspring that carry recombinant chromosomes? (Note: recombinant chromosomes are the product of crossing over). What percentage of F2 offspring would be Aabb?Two strains of S. cerevisae (yeast) are crossed. One has the genotype A B and the other a b. Which statement correctly describes the tetrads that can be produced by one reciprocal exchange between the A and B genes without gene conversion in the dihybrid? A) Recombination occurs at the four-strand stage to produce a tetrad with A B, A B, a B, and a b chromosomes. B) Recombination occurs at the four-strand stage to produce a tetrad with A B, A b, a B, and a b chromosomes. C) Recombination occurs at the two-strand stage to produce a tetrad with A B, A b, a B, and a b chromosomes. D) Recombination occurs at the two-strand stage to produce a tetrad with A b, A b, a B, and a B chromosomes.
- AaBb individuals were crossed to aabb individuals. The following progeny were observed: 5 AaBb, 45 aaBb, 45 Aabb, 5 aabb. Two of the AaBb progeny were crossed to each other. Which of the following would be the nonrecombinant chromosomes in this cross (AaBb X AaBb)?In com, male sterility is controlled by maternal cytoplasmic elements. However, the presence of a nuclear fertility restorer gene (F_) restores fertility to male sterile lines. Using the following cardboard chips, simulate the crosses indicated below. Present your cross to your instructor for checking. After being checked, draw your simulated crosses in the spacesprovided below. Give the genotypes and phenotypes of the offspring in each cross, and properly label the nucleus and the cytoplasm of each individual in the crosses.Big white circular chips Male sterile cytoplasmBig peach circular chips Male fertile cytoplasmSmall peach circular chips FF nucleusSmall half-white-half-peach circular chips Ff nucleusSmall white circular chips ff nucleus a. male sterile female x FF maleExplain your results. b. male sterile female x Ff maleExplain your results.Two genes on chromosome 7 of corn are glossy (g) for leaf texture and ramosa (r), which determines how the ears branch. A test cross between a heterozygous plant for both loci and a doubly recessive plant produces the following progeny and genotypes Phenotype Number of corn kernels counted GR / gr 46 G r / gr 125 g r / gr 45 g R / gr 121 What is the recombination frequency (in %) for the two loci? ___
- During a dihybrid cross involving two linked genes (two-point testcross), 20 flies showed recombinant phenotypes, whereas 480 flies showed the parental phenotypes. How far apart are these linked genes from each other? a. 20 cM b. 7.5 cM c. 4 cM d. 0.04 cM e. 8 cMWhat is a meaning of genetic linkage? How this test is used? Describe the meaning of SNP (single nucleotide polymorphisms) and genetic distance identification which is used in genetic analysis. Knowing that recombination events occur more or less at random along the length of chromosomes, in which case the recombination will occur more frequently between the genes during meiosis: if two genes are closer together two genes are far away from each other there is no impact based on location of two genes. What is a definition of DNA polymorphism and how can this be used for linkage studies? What is a definition of DNA polymorphism and how can this be used for linkage studies?In a diploid plant species, an F1 with the genotype Gg Ll Tt is test-crossed to a pure-breeding recessive plant with the genotype gg ll tt. The offspring genotypes are listed in the table. Genotype Number Gg Ll Tt 621 Gg Ll tt 3 Gg ll Tt 64 Gg ll tt 109 gg Ll Tt 103 gg Ll tt 67 gg ll Tt 7 gg ll tt 626 1600 Calculate the recombination frequency between G and T pair of genes. A. 0.227 B. 0.139 C. 0.454 D. 0.233