According to this diagram, why does the release of estradiol/inhibin stimulate a negative feedback loop on the anterior ptuitary gland?

Understanding Health Insurance: A Guide to Billing and Reimbursement
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Chapter6: Icd-10-cm Coding
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According to this diagram, why does the release of estradiol/inhibin stimulate a negative feedback loop on the anterior ptuitary gland? Isn't the anterior ptuitary gland negatively effected only when estradiol is low, and not high?

Desmolase
Ovaries
hypothalamus
LH
Theca
Cells
GnRH
pituitary
FSH
Aromatase
Granulosa
Cells
Androstenedione
Estradiol/
Inhibin
Transcribed Image Text:Desmolase Ovaries hypothalamus LH Theca Cells GnRH pituitary FSH Aromatase Granulosa Cells Androstenedione Estradiol/ Inhibin
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