Activation of KIT promotes cells to undergo apoptosis

Biology: The Unity and Diversity of Life (MindTap Course List)
14th Edition
ISBN:9781305073951
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Chapter10: Control Of Gene Expression
Section: Chapter Questions
Problem 3CT: Almost all calico cats (one is pictured in FIGURE 10.7B) are female. Why? B When this calico cat was...
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Your friend sends you two cancerous cel| lines to examine and determine possible
mutations.
The results are shown below:
Cell Line
Mutation
WT
none (wild type DNA)
1
a deletion at the same region on both copies of chromosome 4
2
a point mutation in a gene on only one copy of chromosome 7
You learn that cell line 2 is a breast cancer cell line that expresses a mutant version of
a receptor protein called KIT.
Based on this data, which of the following is true ? Select all that apply
Activation of KIT promotes progression through the cell cycle
Activation of KIT releases an inhibition of a cyclin
Activation of KIT causes cells to enter GO
O Activation of KIT promotes cells to undergo apoptosis
Transcribed Image Text:Your friend sends you two cancerous cel| lines to examine and determine possible mutations. The results are shown below: Cell Line Mutation WT none (wild type DNA) 1 a deletion at the same region on both copies of chromosome 4 2 a point mutation in a gene on only one copy of chromosome 7 You learn that cell line 2 is a breast cancer cell line that expresses a mutant version of a receptor protein called KIT. Based on this data, which of the following is true ? Select all that apply Activation of KIT promotes progression through the cell cycle Activation of KIT releases an inhibition of a cyclin Activation of KIT causes cells to enter GO O Activation of KIT promotes cells to undergo apoptosis
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