Activity C: Genetic Mutations: A mutation is a change in the normal DNA sequence of a gene. There are several types of mutations that can occur. A point mutation is when ONE nucleotide on the DNA is changed to a different nucleotide. Some other types of mutations include insertions (a nucleotide is added to the sequence), deletions (a nucleotide is removed from the sequence) and inversions (a piece of DNA is removed and flipped over and then added back into the sequence at the same spot.) 1. Transcribe and translate the "Original Gene" and four mutations of that gene in the table below. The initial location of each mutation is bolded and underlined. 2. Always transcribe the entire DNA sequence into mRNA. Label the 3' and 5' ends for both sequences. 3. When translating from mRNA protein amino acids, stop translation when you reach a stop codon, even if you have not reached the end of the mRNA sequence. End Sequence End 3' TAC TTG TCC GAT CCA ΑΤΑ CCC CGC ATC 5' Original Gene (DNA) mRNA codons Protein amino acids

Activity C: Genetic Mutations: A mutation is a change in the normal DNA sequence of a gene. There are several types of mutations that can occur. A point mutation is when ONE nucleotide on the DNA is changed to a different nucleotide. Some other types of mutations include insertions (a nucleotide is added to the sequence), deletions (a nucleotide is removed from the sequence) and inversions (a piece of DNA is removed and flipped over and then added back into the sequence at the same spot.) 1. Transcribe and translate the "Original Gene" and four mutations of that gene in the table below. The initial location of each mutation is bolded and underlined. 2. Always transcribe the entire DNA sequence into mRNA. Label the 3' and 5' ends for both sequences. 3. When translating from mRNA protein amino acids, stop translation when you reach a stop codon, even if you have not reached the end of the mRNA sequence. End Sequence End 3' TAC TTG TCC GAT CCA ΑΤΑ CCC CGC ATC 5' Original Gene (DNA) mRNA codons Protein amino acids

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter9: Gene Expression And Gene Regulation

Section: Chapter Questions

Problem 20QP: Indicate in which category, transcription or translation, each of the following functions belongs:...

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