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Low doses of aspirin are commonly used to reduce the risk of arterial thrombosis in patients who have suffered myocardial infarction. Which one of the following steps in hemostasis is inhibited by aspirin?
- Aggregation of platelets|
- Adhesion of platelets to collagen
- Production of tissue factor
- Synthesis of von Willebrand factor
- Synthesis of antithrombin III|
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Solved in 3 steps
- Nifedipine is an antihypertension medication that is also used to reduce the workload on the heart. The study below compares the effects of two different types of capsules used to administer the drug to patients (GITSred line, and Cotracten Xblue line). Each graph shows changes with time following initial administra- tion of the capsules. Figure A compares the levels of nifedipine in the blood with each capsule type. The ability of the different cap- sules to reduce workload on the heart by altering blood pressure or heart rate is shown in Figures B and C, respectively. Are elevated plasma levels of nifedipine(above 10 ng/mL) required for the drug to perform its actions? Source: M. J. Brown and C. B. Toal. 2008. Formulation of long-acting nifedipine tablets influences the heart rate and sympathetic nervous system response in hypertensive patients. British Journal of Clinical Pharmacology 65:646652.Nifedipine is an antihypertension medication that is also used to reduce the workload on the heart. The study below compares the effects of two different types of capsules used to administer the drug to patients (GITSred line, and Cotracten Xblue line). Each graph shows changes with time following initial administra- tion of the capsules. Figure A compares the levels of nifedipine in the blood with each capsule type. The ability of the different cap- sules to reduce workload on the heart by altering blood pressure or heart rate is shown in Figures B and C, respectively. Which type of capsule would you expect to have fewer side effects? Source: M. J. Brown and C. B. Toal. 2008. Formulation of long-acting nifedipine tablets influences the heart rate and sympathetic nervous system response in hypertensive patients. British Journal of Clinical Pharmacology 65:646652.Hemostasis is a quick and localized sequence (cascade) of events that helps to prevent a hemorrhage from occurring when a blood vessel is damaged. Hemostasis involves – amongst other things – the formation of a platelet plug. Describe the three steps involved in the formation of a platelet plug. What complication may arise if a platelet plug (thrombus) were to detach and travel through the circulatory system? How does Aspirin help prevent a thrombus from occurring?
- When a blood vessel is injured or severed, the process leading to hemostasis is initiated. The first step in this process is vascular spasm. Platelets contribute to vasospasm in small vessel beds by which of the following mechanisms? (a)Elaboration of vascular endothelial growht factor (b)Presence of actin and mysoin in platelet cytoplasm (c) Production of thromboxanne A2 (d) Release of thrombosthenin (e) Synthesis of prostaglandinsWhich of the following is not an extensive property The combination of equivalent amounts of acids and bases is called? What is the correct sequence of the different stages in blood clotting? I Fibrinogin thrombin fibrin/II Prothrombin thromboplastin Thrombin CaOne of the more common adverse effects of cancerchemotherapy is the destruction of leukocytes. Before hisnext scheduled chemotherapy treatment, a patientundergoes a blood test called an absolute neutrophil count(ANC), which reveals that his neutrophil count is 1900 cells per microliter. Would his healthcare team be likely toproceed with his chemotherapy treatment? Why?
- The content of ATP/ADP was considerably diminished in blood cells which was accompanied with the increase of time of bleeding as a result of hemostasis violation directly during the development of: A. reversible aggregation of thrombocytes B. irreversible aggregation of thrombocytes C. adhesion of thrombocytes D. hemocoagulation E. thromb's retractionIf the life span of an erythrocyte is 120 days, how many times a year would a sickle cell patient need to be given a blood transfusion to ensure a unit of healthy erythrocytes at any given time?Which of the following clotting factors is present in fresh plasma but not in serum? a. XI b. IX c. XIII d. VII
