(ii) What is the significance of Kp? Hence, arrange the three molecules in terms of decreasing affinity to their target.

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter4: Chemical Reactions
Section: Chapter Questions
Problem 4.75P
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AH = - 1.2 kcal/mol;
Kp = 16 nM
OH
1
НО
AH = - 6.0 kcal/mol;
Kp =
= 76 nM
OH
HOllio
AH = - 5.5 kcal/mol;
Kp = 0.5 nM
OH
3
(ii) What is the significance of Kp? Hence, arrange the three molecules in terms of
decreasing affinity to their target.
O=
Transcribed Image Text:AH = - 1.2 kcal/mol; Kp = 16 nM OH 1 НО AH = - 6.0 kcal/mol; Kp = = 76 nM OH HOllio AH = - 5.5 kcal/mol; Kp = 0.5 nM OH 3 (ii) What is the significance of Kp? Hence, arrange the three molecules in terms of decreasing affinity to their target. O=
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