All of the following statements regarding nucleosomes are true EXCEPT A each bead-like structure contains 8 molecules of histones H1, H2A, H2B, H3 and H4 the bead like structures are made up of core histones wrapped around by the DNA strands the histone proteins in the nucleosomes contain positively charged amino acids that interact with the negatively charged DNA the bead like structures are linked to each other by the DNA chain

All of the following statements regarding nucleosomes are true EXCEPT A each bead-like structure contains 8 molecules of histones H1, H2A, H2B, H3 and H4 the bead like structures are made up of core histones wrapped around by the DNA strands the histone proteins in the nucleosomes contain positively charged amino acids that interact with the negatively charged DNA the bead like structures are linked to each other by the DNA chain

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter8: The Structure, Replication, And Chromosomal Organization Of Dna

Section: Chapter Questions

Problem 25QP: Discuss the levels of chromosomal organization with reference to the following terms: a. nucleotide...

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Cell (A) contains 3.1 billion (3.1 x 109) base pairs of DNA. Each nucleosome has about 200 bp of DNAwrapped around the histone core.a. What is the maximum number of nucleosomes that can be present in the cell?b. What is the maximum number of H2A histone protein molecules that can be present in the cell?
Give at least one example of a chromosomal structureor function affected by the following mechanisms formodulating chromatin structure:a. Posttranslational changes of the normal histonesfound in the nucleosome
Which of the following make up a core nucleosome structure? A) about 147 bp of DNA D) A tetramer of histone proteins C) H1 histone E) Answers A and B are correct B) an octamer of histone proteins
4. A previously undiscovered single celled organism was found living at a great depth on the ocean floor. Its nucleus contains only a single, linear chromosome consisting of 7x 106 nucleotide pairs of DNA coalesced with three types of histone-like proteins. The analysis of individual nucleosomes revealed that each unit contained one copy of each protein and that the short linker DNA had no protein bound to it If the entire chromosome consists of nucleosomes (discounting any linker DNA), how many are there and how many total proteins are needed to form them?
Which one of the following statements about nucleosomes is false? a) The DNA double helix wraps around the nucleosome. b) The sequence of amino acid in a histone tail is altered during chromatin remodeling. c) A nucleosome is composed of 8 histone proteins; two copies of each type of histone. d) A large percent of the nucleosome is positively charged.
In eukaryotic cells, the nucleosomal core contains which arrangement of histone proteins? A. two H1, one H2A, one H2B, two H3, and two H4 histone proteins B. two H2B, two H2A, two H3, and two H1 histone proteins C. two H3, two H1, two H2A, and two H2B histone proteins D. two H4, two H3, two H2B, and two H2A histone proteins E. two H2A, two H3, two H4, and two H1 histone proteins
Nucleosomes are the ball-like structures around which the double helix winds. What proteins make up nucleosomes? Group of answer choices hertone histone heterochromatin euchromatin
Define the following terms:a. histonesb. heterochromatinc. euchromatind. intergenic sequencese. tandem repeats
Which of the following statements concerning eukaryotic chromatin is true. Histones have an overall negative charge. Euchromatin is more condensed then heterochromatin. After replication nucleosomes are made up of a mixture of old and new histone proteins. Euchromatin is associated with the centromere and telomere regions. Heterochromatin are regions of active transcription.
. The nucleosomal core in eukaryotes consists of all of the following histone proteins except: histone H1 histone H2A histone H2B histone H3 histone H4
An article entitled “Nucleosome Positioning at the Replication Fork” states: “both the ‘old’ randomly segregated nucleosomes as well as the ‘new’ assembled histone octamers rapidly position themselves (within seconds) on the newly replicated DNA strands” [Lucchini et al. (2002)]. Given this statement, how would one compare the distribution of nucleosomes and DNA in newly replicated chromatin? How could one experimentally test the distribution of nucleosomes on newly replicated chromosomes?
A diploid human cell contains approximately 6.4 billion base pairs of DNA. Q. How many nucleosomes are present in such a cell? (Assume that the linker DNA encompasses 40 bp.)