All the enzymes that participate in the citric acid cycle are located in the mitochondrial matrix, except for which enzyme? 1. aconitase 2. succinate dehydrogenase 3. fumarase 4. malate dehydrogenase
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All the enzymes that participate in the citric acid cycle are located in the mitochondrial matrix, except for which enzyme?
1. aconitase
2. succinate dehydrogenase
3. fumarase
4. malate dehydrogenase
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- Figure 7.11 Dinitrophenol (DNP) is an "uncoupler" that makes the inner mitochondrial membrane "leaky" to protons. It was used until 1938 as a weight-loss drug. What effect would you expect DNP to have on the change in pH across the inner mitochondrial membrane? Why do you think this might be an effective weight-loss drug?The citric acid cycle generates NADH and FADH2, which are then used in the process of oxidative phosphorylation to make ATP. If the citric acid cycle (which does not use oxygen) and oxidative phosphorylation are separate processes, as they are, then why is it that the citric acid cycle stops almost immediately when O2 is removed?The enzymes of the citric acid cycle are located in a. Cytoplasm b. Endoplasmic reticulum c. Mitochondrial matrix d. Nucleus
- What steps in the citric acid cycle have each of the following characteristics? a. The reaction generates FADH 2. b. The organic substrate is oxidized. c. The reaction utilizes NAD +. d. The reaction breaks a carbon–carbon bond.The final outputs of the citric acid cycle include all of the following except what molecule? a. CO2 b. ATP c. Oxaloacetate d. FADH2 e. NADPWhich of these is not true of the citric acid cycle?a. The citric acid cycle includes the prep reaction.b. The citric acid cycle produces ATP by substrate-level ATPsynthesis.c. The citric acid cycle occurs in the mitochondria.d. The citric acid cycle produces two ATP per glucose molecule.
- Each turn of the citric acid cycle directly produces ________. a. 2 carbon dioxide molecules b. 2 ATP molecules c. 3 NADH and 1 FADH 2Which of the following reactions DOES NOT take place during the citric acid cycle? The energy investment phase, whereby two phosphates are added to glucose to make Fructose-1,6-biphosphate. The hydrolysis of fumarate to make malate. FAD retrieves hydrogen ions and electrons from succinate to form FADH2 and fumarate. Carbon dioxide is released when alpha-ketoglutarate is transformed to Succinyl CoA.Which complex of the mitochondrial electron transport chain accepts electrons directly from NADH (the reduced form of nicotinamide adenine dinucleotide)? NADH dehydrogenase (complex I) FADH2 dehydrogenase (complex II) cytochrome b-c1 (complex III) cytochrome c oxidase (complex IV) the ATP synthase complex Chapter 14, Pg. 78
- Which of the following is the second step of Citric Acid Cycle? Select one: a. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH b. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH c. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH d. Malate is oxidized to become oxaloacetate forming NADH e. Fumarate is combined with water to become Malate f. Citrate is rearranged to become Isocitrate g. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide h. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) i. Succinate is oxidized to become fumarate forming FADH2Where does the citric acid cycle take place in the cells of eukaryotic organisms? Mitochondrial matrix Mitochondrial intermembrane space Mitochondrial inner membrane CytoplasmWhat products of the citric acid cycle are needed for the electron transport chain? A) NADH/H+NADH/H+ and FADH2FADH2 B) NADH/H+NADH/H+ and HS−CoAHS−CoA C) FADH2FADH2 and HS−CoA
