Answer the following questions: (Provide reference and in-text citation) 1. Which disease is characterized by the symptoms experienced by Patient X? Correlate her medical information and travel history to the disease. 2. Explain the pathology of the disease. 3. Which virus could have caused the disease? How did she contract the virus? 4. Which of her symptoms indicate early signs of shock? Which of her symptoms point to hemorrhagic manifestations? 5. Enumerate laboratory methods that can be used to diagnose the disease or detect the virus. 6. How is the disease treated and controlled/prevented?
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- A 48-year-old businessman, presents at the emergency room with a 12-day history of headache, myalgia, nausea, and vomiting. Patient history reveals that the patient is a consulting engineer for the tropical area. On his latest trip, he failed to take his prophylaxis for malaria. According to his general physician’s records, all his immunizations are up to date. His fever was 39°C at the time of initial examination, but alternated with periods of extreme cold and cyanosis. A complete blood count was ordered, along with parasite examination and urinalysis. What parasite do you suspect? Which morphological factor will be important in deciding the species of this organism? Which morphological form you may observe in the peripheral blood of this patient? How did the patient contract this parasitic infection? Why this species can cause much more serious result than other species among this organism? Please list name of three parasites that lead to anemia as the main symptoms, and their…JA is a 28-year-old female who presents with a rash over her arms, buttocks, lower back, and legs. The small pink papules are at the hair follicles. She and a friend completed a "mud run" three days ago. What would you recommend? JA did as you instructed for the past several days and while some areas improved, others are worse, pink or red papules with pustules, and she has a low-grade fever.A 50-year-old patient was hospitalized in the infectious department of the district hospital on the 4th day of illness with suspected typhoid-paratyphoid disease. The disease began with a gradual rise in temperature, which reached a maximum level of 39 degrees C on the 3rd day. Complaints of headache, loss of appetite, general weakness, constipation, bloating and flatulence. From the anamnesis: a family member of the patient 2 months ago fell ill with typhoid fever. Objectively: remitting fever, pale skin, moderately bloated abdomen, slight enlargement of the liver and spleen, mental retardation. There is no rash. 1-What serological tests should be used to establish the etiology of typhoid? 2-What are the features of serological diagnosis in the early stages of the disease? What measures should be taken to avoid false-negative serological results in the early stages? 3-What serological reactions are used for serological diagnosis of typhoid fever and paratyphoid fever? Compare and…
- The patient was an 80-year-old female who 10 days previously had had a cystocele repair performed. At the time of the hospital admission, a urine culture was obtained and revealed >100,000 CFU/ml of an Escherichia coli strain that was susceptible to all antimicrobial agents against which it was tested. Postoperatively, she began a 7-day course of oral cephalexin. She was discharged after an uneventful postoperative course of 3 days. Ten days postoperatively, she presented with a 3-day history of diarrhea. The patient noted multiple watery, loose stools without blood, crampy abdominal pain, and vomiting. She presented with a temperature of 38.2 degrees C, pulse rate of 90/min, respiration rate of 20/min, and blood pressure of 116/53mm Hg. Her white blood cell count was normal, but a large number (53%) of immature polymorphonuclear cells were seen. Physical examination, electrolytes, liver enzymes, and lipase were all within normal limits. Cultures for Salmonella, Shigella, Yersinia,…A 10-year-old boy was brought in by his father for evaluation of crampy abdominal pain, nausea and mild diarrhoea that had persisted for approximately 2 weeks. On the day before evaluation, the boy reported to his parents that he passed a large worm into the toilet during bowel movement. He flushed the worm before the parents could see it. Physical examination was completely unremarkable. The boy had no fever, cough or rash and did not complain of anal pruritus. His travel history was unremarkable. Examination of a stool specimen revealed the diagnosis. The boy is infected by which kind of parasite? Was this patient at risk of autoinfection? Why? Can this parasite cause extraintestinal symptoms? What are the major complications caused by the parasite?A 13-year-old male, who recently immigrated with his parents from Romania, presents with a 2 day history of fever, sore throat and difficulty breathing. Immunization records are unavailable. On physical exam, temperature is 102°F (38.9°C). A grayish white membrane is seen in the oropharynx. There is enlargement of the cervical lymph nodes, resulting in a bull neck. QUESTIONS: What pathogen caused the disease? What is the morphology and staining characteristics of the pathogen? What is its most important virulence factor? Discuss: Criteria for toxin production (lysogeny, iron…) Properties of the toxin Mode of action How does the pathogen spread? What risk factors are associated with the infection? What are the clinical symptoms of the disease? What are the possible complications from the disease? How is the disease diagnosed? Discuss: Specimen selection Microscopic observation Culture Virulence test What is the best treatment for the disease? How can the disease be prevented?…
- Answer by listing only the name of the disease. Some questions will require the name of the organism. A 37 year old woman presents with muscular pain and flu-like symptoms. She tells you she is generally a healthy woman, as she is an avid hiker. Upon closer inspection, you notice a spotted rash formed on her ankles and wrists and proceed to ask her if anything unusual occurred on her last hike. She says no, outside of the occasional bug bites that come with hiking. What has the woman contracted? 2.A 28 year old woman presents with a swollen eyelid that is emitting a yellow discharge. After finding out the causative agent is Staphylococcus aureus, you prescribe penicillin and tell the patient to check back with you after 1 week. You tell her to be careful, as this condition is extremely contagious. Which eye condition does this patient have?24-year-old male, drug user (marijuana) and hookah user, he comes to the emergency room with a chronic, productive cough, a viscous sputum, and a loss of approx. 15 lbs of weight. Then he started with dyspnea when walking, stabbing pain in right chest, night sweats. He denies quantified fever spikes. RT: 120-80Mmg, FC 80latxmts, FR: 16, SATO2 98%. Symmetric chest, Lungs: absence of vesicular murmur in the lower 2¨ thirds of the right hemithorax, and dullness in this area, no added noises or rales. a) Possible diagnoses b) What studies would you request from this patient. c) Treatments according to your diagnostic approaches.22-year-old woman has had recurrent episodes of diarrhea, crampy abdominal pain, and slight fever over the last 2 years. At first the episodes, which usually last 1 or 2 weeks, were several months apart, but recently they have occurred more frequently. Other symptoms have included mild joint pain and sometimes red skin lesions. On at least one occasion, her stool has been guaiac-positive, indicating the presence of occult blood. Colonoscopy reveals several sharply delineated areas with thickening of the bowel wall and mucosal ulceration. Areas adjacent to these lesions appear normal. Biopsies of the affected areas show full-thickness inflammation of the bowel wall and several noncaseating granulomas. 1. What is the most likely diagnosis? 2. What are the common complications of this disease?
- A 33-year-old man presents to his primary doctor complaining of high fever and chills that lasted for one week. He complained that his chest hurts when he coughs, and the sputum has a greenish tint. During this time, the patient has had an unproductive cough and shortness of breath when he exerts himself. He has a general feeling of malaise and has noticed a decrease in appetite. He has been using an over-the-counter cold medicine for symptom relief, but symptoms return when the medication wears off. The patient has been working outside on a construction job this winter. He is under a lot of stress with the recent move into a new apartment with his pregnant wife. Physical examination (PE): Patient breathing pattern is rapid and shallow, with some dyspnea during deep breaths. Cough produces green/yellow sputum. Vital signs: Temperature: 40°C, Pulse: 90/min, Respiratory rate 25/min, Blood pressure: 112/70 mm Hg BMI=20 Laboratory Test Blood cultures : Positives with Streptococcus…A 63-year-old international telecommunications executive visits your office with complaints of a high fever. The fever is not constant, but intermittent. When you press him for details he estimates that every three days or so he suffers these debilitating “sweats”. He usually has headaches and muscle aches during the episodes. They keep him home from work. After half a day or so, he feels better. He reports that he has experienced these episodes for about two months. What is the name of the condition you suspect? What is the causative organism? Is this pathogen eukaryotic or prokaryotic? What should be your first question about the patient’s history? What are the two main places in the human body that are exploited by the causative organism in this disease? Can this individual transmit this infection to others? Why or why not? How should this patient be treated (general treatment procedures/explain)?A 44-year-old Nigerian man was admitted as an emergency while visiting relatives in England. His symptoms include abdominal pain, sweating, rigors and vomiting. Had been treated twice for malaria but had never taken malarial prophylaxis. Examination revealed he is ill and jaundiced, temperature of 39.2°C, blood pressure was 90/70, but no signs of visceral perforation. Differential diagnosis include– occult gastrointestinal bleeding, septicaemia, hepatitis or recurrence of malaria Emergency investigations: normal haemoglobin (140g/l), white cell count of 6.1 x 109/l, sickle-cell anaemia (excluded), thick blood film Treatment: intravenous quinine. Unfortunately the Px rapidly deteriorated over the next 30h leading to cardiac arrest. Post-mortem diagnosis: Cerebral Malaria QUESTION: 1.What is your final diagnosis here? Explain the cause of his disease. 2. What drug, dosage form, schedule, and duration of therapy are best for treating patients with this condition?