Questions: What were the most significant findings associated with this patient’s complete blood count (CBC) and differential? What is the diagnosis of the patient? In this leukemia- Chronic phase, it has to be distinguished from the following disease/disorder: Give at least two. A) B)

Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter2: Basic Hematology
Section2.9: White Blood Cell Differential Count
Problem 2.1CS
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Questions:

  1. What were the most significant findings associated with this patient’s complete blood count (CBC) and differential?
  2. What is the diagnosis of the patient?
  3. In this leukemia- Chronic phase, it has to be distinguished from the following disease/disorder: Give at least two. A) B)
A 29 year old female who had a routine CBC done by her primary care physician. The blood was
collected as an outpatient on a Saturday morning, and brought to our lab by a routine courier that afterno
One previous CBC result on this lady from several years earlier was essentially normal. CBC result shown be
Manual Diff
Patient
Reference Range
Results
Patient
Results
WBC
363.14
4.5-10.5 x 103/uL
Neuts
33.5%
RBC
3.21
4.2-5.8 x 106/uL
Bands
21.0
Hgb
9.8
13.5 -16.5 g/di
Lymphs
1.5%
Hct
31.8
40-49.0%
Monos
3.5%
MCV
99.1
80-100 fl
Eos
3.5%
PLT
159
150-450 x 10/µL
Basos
3.5%
IANC
173.84
1.6-8.40 x 10/µL
Metas
9.5%
Myelos
12.0%
Promyelos 8.0%
Blasts
4.0%
Cytogenetic analysis showed
abnormal clone characterized by the
Philadelphia chromosome
translocation, t(9;22).
The BCR/ABL gene rearrangement was
detected by FISH.
Transcribed Image Text:A 29 year old female who had a routine CBC done by her primary care physician. The blood was collected as an outpatient on a Saturday morning, and brought to our lab by a routine courier that afterno One previous CBC result on this lady from several years earlier was essentially normal. CBC result shown be Manual Diff Patient Reference Range Results Patient Results WBC 363.14 4.5-10.5 x 103/uL Neuts 33.5% RBC 3.21 4.2-5.8 x 106/uL Bands 21.0 Hgb 9.8 13.5 -16.5 g/di Lymphs 1.5% Hct 31.8 40-49.0% Monos 3.5% MCV 99.1 80-100 fl Eos 3.5% PLT 159 150-450 x 10/µL Basos 3.5% IANC 173.84 1.6-8.40 x 10/µL Metas 9.5% Myelos 12.0% Promyelos 8.0% Blasts 4.0% Cytogenetic analysis showed abnormal clone characterized by the Philadelphia chromosome translocation, t(9;22). The BCR/ABL gene rearrangement was detected by FISH.
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Prompt 1: Explain in detail the pathogenesis of a DVT (Deep Vein Thrombosis) and how it can lead to a PE (Pulmonary Embolism) 

Prompt 2: Research and list all the possible treatment options for a DVT

Please correlate your responses to Samantha's  case. Also, note that content in this case scenario incorporates topics from Chapters 14 and 15.  

 

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