appropriate symptoms. Urticaria Angioedema Eczema A. Activation of mast cells on the skin B. Prolonged skin response C. Activation of mast cells in deeper subcutaneous tissue 2. Match the chemical found in granules with its function. Leukotrienes Histamine Prostaglandin TNF-a Chymotryptase, tryptase, neutral proteases A. Induces vascular permeability B. Respond in later stages of inflammation to trigger smooth muscle contraction, constriction of airways, and mucous membranes C. Increases expression of adhesion molecules promoting WBC movement

Essentials of Pharmacology for Health Professions

7th Edition

ISBN:9781305441620

Author:WOODROW

Publisher:WOODROW

Chapter16: Gastrointestinal Drugs

Section: Chapter Questions

Problem 6CRQ

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1. Match the allergic skin reaction with the appropriate symptoms.

	Urticaria
	Angioedema
	Eczema

A.	Activation of mast cells on the skin
B.	Prolonged skin response
C.	Activation of mast cells in deeper subcutaneous tissue

2. Match the chemical found in granules with its function.

	Leukotrienes
	Histamine
	Prostaglandin
	TNF-a
	Chymotryptase, tryptase, neutral proteases

A.	Induces vascular permeability
B.	Respond in later stages of inflammation to trigger smooth muscle contraction, constriction of airways, and mucous membranes
C.	Increases expression of adhesion molecules promoting WBC movement
D.	Acts as a chemoattractant of neutrophils
E.	Leads to the breakdown of extracellular matrix proteins

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