Arginine has three ionizable groups. The pk of a-COOH is 2.18; a-NH 3+, 9.09; and the R-group, 13.20. What is the charge of arginine at pH = 12? O O O -2

General, Organic, and Biological Chemistry
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Author:H. Stephen Stoker
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Chapter20: Proteins
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Problem 20.50EP: Arginine exists in two high-pH forms instead of the usual one. Explain why.
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Arginine has three ionizable groups. The pk of a-COOH is 2.18; a-NH 3 +, 9.09; and the R-group, 13.20.
What is the charge of arginine at pH = 12?
0
-2
Transcribed Image Text:Arginine has three ionizable groups. The pk of a-COOH is 2.18; a-NH 3 +, 9.09; and the R-group, 13.20. What is the charge of arginine at pH = 12? 0 -2
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