fast answer pls Ascil is an activating transcription factor containing a DNA binding domain and an activationdomain. Ascl1 induces neuronal differentiation. A truncated Ascl1 lacking the DNA bindingdomain but with an intact activation domain will:O Bind to DNA, activate transcription, and differentiate cells into neuronsO Bind to DNA, not activate transcription, and not differentiate cells into neuronsO Not bind to DNA, activate transcription, and differentiate cells into neuronsNot bind to DNA, not activate transcription and differentiate cells into neuronsO Not bind to DNA, not activate transcription, and will not differentiate cells into neurons

Some transcription factors bind to a DNA promoter sequence near the transcription start site and…

Ascll is an activating transcription factor containing a DNA binding domain and an activation domain. Ascil induces neuronal differentiation. A truncated Asci1 lacking the DNA binding domain but with an intact activation domain will: Bind to DNA, activate transcription, and differentiate cells into neurons Bind to DNA, not activate transcription, and not differentiate cells into neurons Not bind to DNA, activate transcription, and differentiate cells into neurons O Not bind to DNA, not activate transcription and differentiate cells into neurons O Not bind to DNA, not activate transcription, and will not differentiate cells into neurons

Ascll is an activating transcription factor containing a DNA binding domain and an activation domain. Ascil induces neuronal differentiation. A truncated Asci1 lacking the DNA binding domain but with an intact activation domain will: Bind to DNA, activate transcription, and differentiate cells into neurons Bind to DNA, not activate transcription, and not differentiate cells into neurons Not bind to DNA, activate transcription, and differentiate cells into neurons O Not bind to DNA, not activate transcription and differentiate cells into neurons O Not bind to DNA, not activate transcription, and will not differentiate cells into neurons

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter16: Regulation Of Gene Expression

Section: Chapter Questions

Problem 6TYK

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Select all of the processes that could be involved in a transcriptional repressor leading to decreased gene expression. a. chromatin remodelling complex responds to tail modification by removing nucleosomes . b. transcription factor binding attracts acetyltransferase enzymes . C. transcription factor binding attracts deacetylase enzymes . D. chromatin remodelling complex responds to tail modification by shifting nucleosomes to a denser grouping. E. DNase cuts the exposed DNA to prevent transcription initiation F. RNA polymerase is unable to recognize the promoter because of the dense chromatin configuration
For each of the terms in the left column, choose thebest matching phrase in the right column.a. basal factors 1. organizes enhancer/promoter interactionsb. repressors 2. pattern of expressiondepends on which parenttransmitted the allelec. CpG 3. activates gene transcriptiontemporal- and tissue-specificallyd. imprinting 4. site of DNA methylatione. miRNA 5. identifies DNA-binding sitesof transcription factorsf. coactivators 6. bind to enhancersg. epigenetic effect 7. bind to promotersh. insulator 8. bind to activatorsi. enhancer 9. prevents or reduces geneexpression posttranscriptionallyj. ChIP-Seq 10. heritable change in geneexpression not caused byDNA sequence mutation
Which of the following is true of CpG islands? a. They are methylated near promoters of actively transcribed genes. b. They are unmethylated near promoters of actively transcribed genes. c. Acetylation of CpG islands leads to repression of transcription. d. CpG islands code for RNA molecules that activate transcription.
What is the role of general transcription factors? GTFs bind to enhancers or silencers and regulate transcription GTFs bind to the core promoter and allow transcriptional initiation GTFs are cis-acting regulatory sequences GTFs regulate the length of the mRNA GTFs are part of the RNA polymerase II holoenzyme, and control transcription initiation
there is the statement: "Both stem cells and specialized cells have all the same genes. They differ in the regulation of those genes and express very different sets of genes ". Which one of the following explanations best accounts for this difference in stem cell and specialized cell gene expression? A. Stem cells and specialized cells have different activators and repressors that affect transcription B. Stem cells and specialized cells have different promoter sequences for their genes, thus affecting transcription C. Stem cells and specialized cells have different ribosomes that affect translation D. Stem cells and specialized cells use different start codons on mRNAs, thus affecting translation
For each statement about gene expression mechanisms, choose the correct end to the sentence. For each gene, the template strand for transcription is determined by…. The direction of translation is determined by…… The tissue-specificity of protein production is determined by…. choices: a. location of the start codon b. location of the promoter c. direction of polymerization by RNA polymerase d. none of these e. direction of movement of ribosomes f. overall orientation of the chromosome
A translocation mutation results in a silencer being inserted just upstream of the promoter of a gene (Gene X). How would you predict the expression of gene X be affected by this mutation? Gene X will not be expressed in any cell that has this mutation Gene X will not be expressed in any cell that has this mutation and the appropriate repressor protein Gene X will be expressed in any cell that has this mutation Gene X will be expressed in any cell that has this mutation and the appropriate repressor protein
which of the following correctly describes how protein kinase A can activate genes? A: nuclear protein kinase A is activated by cAMP to phosphorylate general transcription factors B: cytosolic protein kinase A is activated by cAMP to release the catalytic subunits, which move into the nucleus and phosphorylate CREB C: cytosolic protein kinase A is activated by cAMP to release the catalytic subunits, which move into the nucleus and phosphorylate general transcription factors D: G protein-coupled receptors may be desensitized by serine phosphorylation
1. Trithorax group proteins silence genes by* a. trimethylating histone 3 at lysine residue 2. b. trimethylating histone 4 at lysine residue 2. c. trimethylating histone 3 at lysine residue 4. d. trimethylating histone 4 at lysine residue 4. 2. Bonding of which ligand does NOT result to transcription activation?* a. fibroblast growth factor b. jagged protein c. TGF-β family d. Wnt family
Which of the following statements is most consistent with the pattern of gene expression shown in the given graph? (A) Repressors that bind to a regulatory sequence of Gene X are present in brain tissue but not in heart tissue. (B) Gene X is located within heterochromatin in brain tissue and within euchromatin in heart tissue. (C) Small RNAs that help degrade Gene X mRNA are present in brain tissue but not in heart tissue (D)Activators that bind to an enhancer of Gene X are present in brain tissue but not in heart tissue.
The RB (retinoblastoma) protein normally [ Select] ["keep a transcription factor in an inactive state", "keep a transcription factor in an active state", "keep the CDK in a phosphorylated state", "block the function of the APC"] ...But it can be deactivated by [ Select ] ["ubiquitination", "methylation", "phosphorylation", "the use of a GAP"] .Mutations in Rb can lead to cancer because these mutations [ Select ] ["result in constitutive transcription leading to promotion of the cell cycle", "keep CDKs off", "deactivate p53", "increase the production of growth hormones"] PLEASE SELCET THE CORRECT ONE FOR SECTION ONE . EACH SENTECNE HAVE 4 SECTION TO PICK FROM.
Q. Which of the following describes the role of acetylation during the chromatin remodeling that accompanies gene expression? A. It adds an acetyl group to the DNA of a promoter sequence. B. It adds an acetyl group to the histone protecting the promoter region of a gene. C. It adds an acetyl group to the cyotsine nucleotides of DNA. D. It adds an acetyl group to the histone protecting the transcription unit of a gene.