Xist gene is located in a 450 kb region of DNA called the X inactivation center (XIC) and is transcribed only fromthe future inactive X chromosome. The Xist noncoding RNA (ncRNA) triggers X inactivation by coating the Xchromosome that produces it and recruiting enzymes that allow Barr body formation. How one X chromosome ischosen to express Xist is unknown.Active XInactive XXistXIC• Histone modifying proteins~ Xist ncRNAWhich of the following scenarios will cause the maternal X chromosome to condense into a Barr body?Select all that apply.O Histone deacetylation of the promoter region of paternal Xist geneDNA methylation of the promoter region of patemal Xist geneO Gain-of-function mutation in the repressor of Xist transcriptionO Transcriptional repression of the maternal Xist geneO Deletion of Xist promoter on maternal X chromosomeDeletion of XIC on maternal X chromosome

Name: Xist gene is located in a 450 kb region of DNA called the X inactivat
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Description: Xist gene is located in a 450 kb region of DNA called the X inactivation center (XIC) and is transcribed only fromthe future inactive X chromosome. The Xist noncoding RNA (ncRNA) triggers X inactivation by coating the Xchromosome that produces it an

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Which of the following scenarios will cause the maternal X chromosome to condense into a Barr body? Select all that apply. Histone deacetylation of the promoter region of paternal Xist gene O DNA methylation of the promoter region of paternal Xist gene O Gain-of-function mutation in the repressor of Xist transcription O Transcriptional repression of the maternal Xist gene O Deletion of Xist promoter on maternal X chromosome O Deletion of XIC on maternal X chromosome

Which of the following scenarios will cause the maternal X chromosome to condense into a Barr body? Select all that apply. Histone deacetylation of the promoter region of paternal Xist gene O DNA methylation of the promoter region of paternal Xist gene O Gain-of-function mutation in the repressor of Xist transcription O Transcriptional repression of the maternal Xist gene O Deletion of Xist promoter on maternal X chromosome O Deletion of XIC on maternal X chromosome

Biology: The Unity and Diversity of Life (MindTap Course List)

14th Edition

ISBN:9781305073951

Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr

Publisher:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr

Chapter10: Control Of Gene Expression

Section: Chapter Questions

Problem 3CT: Almost all calico cats (one is pictured in FIGURE 10.7B) are female. Why? B When this calico cat was...

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Q. Both histone deacetylase (HDAC) and Xist would be on a list of genes involved in X chromosome inactivation. In which of the following ways would the histone deacetylase gene be similar to the Xist gene? A. They would both be transcribed. B. They would both be translated. C. They would both undergo intron splicing. D. They would both be transported to the cytoplasm after transcription.
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