At what position, and on what ring, would you expect the following substances to undergo electrophilic substitution? Draw the structure and indicate with asterisks the expected position on the ring. H Br
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- At what position, and on what ring, would you expect the following substances to undergo electrophilic substitution?Draw the structure and indicate with asterisks the expected position on the ring.At what position, and on what ring, would you expect the following substance to undergo electrophilic substitution?Draw the structure and indicate with asterisk(s) the expected position of electrophilic substitution.What is the slow (rate-determining) step in any electrophilic aromatic substitution reaction? Please provide a detailed explanation.
- The compound below undergoes electrophilic aromatic substitution to form a monosubstituted product. At which position will the electrophile going to attack?Aromatic heterocycles can undergo electrophilic aromatic substitution like benzene. Groups attached to the heterocycle can therefore have similar directing effects as they can on benzene. Keeping this in mind, consider the following reaction, where E+ is a general electrophile: a) Draw all relevant resonance structures for the intermediate of each product b) Based on your answers to part a), which product do you expect to be the major product and why? (2 points)c) If you performed this reaction in the laboratory, which instrumental technique (ex: 1H NMR, IR, Mass Spectrometry) would be best to determine which product you obtained of the three and why?Which carbon will be the best site for electrophilic aromatic substitution?
- Highlight each of the positions on the benzene ring that you expect will be most likely to react by electrophilic aromatic substitution. Am I correct?Usually at the 2- or 3- position, Thiophene undergoes electrophilic aromatic substitution. Draw the intermediates and all resonance structures for the reaction at each position, and then decide what position should be more reactive depending on your intermediates.Predict the most likely sites of electrophilic aromatic substitution in each of the following molecules.
- List the following order of increasing reactivity in an SN1 reactionArrange the following three compounds below with regard to their ease of undergoing an SN1 reaction. Draw the relevant structure(s) to justify. Place the fastest one on topWhich position(s) on the ring would substitution occur when the aromatic compound shown undergoes bromination with Br2 , FeBr3 (when necessary)